{"id":"W6902235049","doi":"10.6084/m9.figshare.22726895","title":"Efficacy, safety, and tolerability of ulotaront (SEP-363856, a trace amine-associated receptor 1 agonist) for the treatment of schizophrenia and other mental disorders: a systematic review of preclinical and clinical trials","year":2023,"lang":"en","type":"article","venue":"Figshare","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Tolerability; Adverse effect; Schizophrenia (object-oriented programming); Clinical trial; Systematic review; Meta-analysis; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005720054,0.001188244,0.008333409,0.005579518,0.00052324,0.001798967,0.001529407,0.001552199,0.004216425],"category_scores_gemma":[0.01759956,0.0006893054,0.008107373,0.005675029,0.000712051,0.001455085,0.001032494,0.0009195164,0.0002932515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002219339,"about_ca_system_score_gemma":0.006443232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005272571,"about_ca_topic_score_gemma":0.01722168,"domain_scores_codex":[0.9962062,0.0010857,0.001630166,0.00029058,0.0006823243,0.0001049439],"domain_scores_gemma":[0.9890807,0.007130969,0.002346147,0.0001386488,0.001150265,0.0001532444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0004764543,0.00001589651,0.0002936076,0.9561151,0.01021597,0.0000649312,0.00009189056,0.00007456243,0.0002657788,0.0001178813,0.0006706285,0.03159735],"study_design_scores_gemma":[0.0009302152,0.0008215003,0.004415392,0.7581189,0.213346,0.0004761172,0.0002541809,0.0001740077,0.00052598,0.0004108749,0.02046429,0.00006256224],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001335353,0.9975242,0.0001129701,0.000131254,0.00005701141,0.0002805911,0.0003144912,0.000006910711,0.0002371858],"genre_scores_gemma":[0.01644303,0.981813,0.0005225447,0.0003735581,0.00005133086,0.0004238667,0.0002262687,0.000005294974,0.0001410988],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008333409,"threshold_uncertainty_score":0.03025085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1651473189780824,"score_gpt":0.4464868982841201,"score_spread":0.2813395793060376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}