{"id":"W6902238632","doi":"10.6084/m9.figshare.26777941","title":"Additional file 1 of Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Saskatchewan","funders":"","keywords":"Progressive supranuclear palsy; Sequence analysis; Genetic analysis; DNA sequencing; Exome sequencing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001200298,0.001388968,0.001435859,0.002889249,0.001482778,0.00157515,0.002271592,0.00180239,0.8407545],"category_scores_gemma":[0.01625513,0.0008106495,0.001257399,0.003584502,0.0004430712,0.00126613,0.001156628,0.001309038,0.1382115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007976997,"about_ca_system_score_gemma":0.001518684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007512145,"about_ca_topic_score_gemma":0.01315825,"domain_scores_codex":[0.9992425,0.0001054082,0.0001028862,0.0002587264,0.0001393612,0.0001509965],"domain_scores_gemma":[0.983594,0.01339228,0.000768701,0.0007010626,0.0009156555,0.0006283227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0005475564,0.0001510862,0.005000948,0.003434736,0.000132345,0.0004538376,0.0001251978,0.0007192313,0.001075314,0.001262883,0.9773065,0.009790256],"study_design_scores_gemma":[0.009755196,0.0005833307,0.1039788,0.004340621,0.0006725871,0.004023646,0.0006338441,0.003451708,0.003731289,0.02499874,0.8434388,0.0003914482],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.000419462,0.00003047735,0.000435659,0.00009865069,0.00003949628,0.00003736025,0.9979262,0.0002857019,0.0007269721],"genre_scores_gemma":[0.009584045,0.0001752407,0.004750885,0.000819904,0.0001442831,0.0007424252,0.9767103,0.001116979,0.005955905],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.8407545,"threshold_uncertainty_score":0.2271443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0136627747925927,"score_gpt":0.233812996328056,"score_spread":0.2201502215354633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}