{"id":"W6903054236","doi":"10.1021/ol061036k.s003","title":"1,4-Diazepinone and Pyrrolodiazepinone\\nSyntheses via Homoallylic Ketones from\\nCascade Addition of Vinyl Grignard\\nReagent to α-Aminoacyl-β-amino Esters","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stantec (Canada)","funders":"","keywords":"Intramolecular force; Moiety; Olefin fiber; Ketone; Cascade; Reagent","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00009023869,0.0004660814,0.0006444213,0.0001764659,0.000139489,0.00004430536,0.0004810833,0.0003078643,0.248052],"category_scores_gemma":[0.001042812,0.0003736541,0.0001947442,0.0001573613,0.00009556163,0.000345691,0.0002923122,0.0001694609,0.0009556152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007045475,"about_ca_system_score_gemma":0.00005725843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006444236,"about_ca_topic_score_gemma":0.00002326965,"domain_scores_codex":[0.9976498,0.00009651219,0.0005908766,0.0007619665,0.0003584905,0.0005423407],"domain_scores_gemma":[0.9969279,0.001657665,0.000366852,0.0005348533,0.0001544795,0.0003582778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002014209,0.0002484892,0.001125313,0.0004018121,0.0003285556,0.00005118455,0.0007844293,0.000004676373,0.7905618,0.000008319489,0.1062765,0.1000075],"study_design_scores_gemma":[0.0009387195,0.000118471,0.04626078,0.002877336,0.0000878154,0.00002309687,0.0001569472,0.00005019816,0.8754814,0.000117423,0.0732263,0.0006615007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7215146,0.001137653,0.00003542104,0.001496725,0.000124625,0.0003767278,0.2717617,0.0002232194,0.003329293],"genre_scores_gemma":[0.9891332,0.0001046528,0.0003359065,0.0003951023,0.0004393822,0.0004857752,0.008569067,0.00007314525,0.0004637866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2676186,"threshold_uncertainty_score":0.9998716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03044481794373299,"score_gpt":0.2535442534814735,"score_spread":0.2230994355377405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}