{"id":"W6903054236","doi":"10.1021/ol061036k.s003","title":"1,4-Diazepinone and Pyrrolodiazepinone\\nSyntheses via Homoallylic Ketones from\\nCascade Addition of Vinyl Grignard\\nReagent to α-Aminoacyl-β-amino Esters","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stantec (Canada)","funders":"","keywords":"Intramolecular force; Moiety; Olefin fiber; Ketone; Cascade; Reagent","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117403,0.0003263549,0.0001563921,0.0001816048,0.0001333507,0.0001430653,0.0002598929,0.0001299643,0.002451615],"category_scores_gemma":[0.00007789271,0.0001427165,0.0001519613,0.0001566639,0.0001510172,0.0003220543,0.0002572791,0.0003938914,0.0009516372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003470418,"about_ca_system_score_gemma":0.000394444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007811516,"about_ca_topic_score_gemma":0.002096889,"domain_scores_codex":[0.9999322,0.000004543949,0.000004822444,0.00001443839,0.00001572864,0.00002832157],"domain_scores_gemma":[0.9999654,0.00000242757,0.000006934643,0.00000590852,0.000006675319,0.00001264147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000118264,0.00004711621,0.000128867,0.0001692965,0.00001052086,0.0004075541,0.0001170668,0.0003497287,0.987971,0.00253008,0.0003314779,0.00781906],"study_design_scores_gemma":[0.00003372863,0.0003148548,0.0008978749,0.000009235432,0.000009927154,0.0002610173,0.0000354805,0.0005147504,0.9853168,0.0002468707,0.01234559,0.00001384775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9572535,0.002533863,0.01553207,0.0001513065,0.00009465324,0.0001744423,0.001181105,0.0003310232,0.0227481],"genre_scores_gemma":[0.9767453,0.0024801,0.00983121,0.0000394045,0.00001166556,0.00008888345,0.0009494864,0.00003733434,0.009816716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002451615,"threshold_uncertainty_score":0.00820154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03044481794373299,"score_gpt":0.2535442534814735,"score_spread":0.2230994355377405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}