{"id":"W6903256851","doi":"10.1021/ol005790w.s001","title":"Thiopyran Route to Polypropionates: \\nAldol Diastereoselectivity of Linear and\\nTwo-Directional Iterative Homologations","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Aldol reaction; Aldehyde; Thiopyran; Adduct; Alkene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006329048,0.0001612383,0.00019912,0.00003972247,0.00008398732,0.00001386007,0.0001614126,0.0001248673,0.1412607],"category_scores_gemma":[0.003049956,0.0001242324,0.00006353147,0.0001517147,0.00002213124,0.0000895655,0.0001348985,0.000111751,0.0001991648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008157413,"about_ca_system_score_gemma":0.00009718288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008244221,"about_ca_topic_score_gemma":0.000008412963,"domain_scores_codex":[0.9990439,0.00003729385,0.0002116255,0.0003342,0.0001816242,0.0001912973],"domain_scores_gemma":[0.9985489,0.0007764844,0.0001074458,0.0002795019,0.0001631292,0.000124551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003809766,0.0000839619,0.001048579,0.0001876882,0.00006858353,0.000004478521,0.0005801343,0.000001373715,0.9716583,0.0000178743,0.005394716,0.02091623],"study_design_scores_gemma":[0.0002997694,0.00002065521,0.001827791,0.0009315821,0.00001116032,0.00003350319,0.000049216,0.00003696441,0.9858868,0.0001083168,0.01061723,0.0001770196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.4515616,0.0003199907,0.000659593,0.002515764,0.000171496,0.0004832528,0.5107237,0.0005290678,0.03303561],"genre_scores_gemma":[0.9900078,0.000001730756,0.003715584,0.00006049478,0.0002521019,0.0001361804,0.002060608,0.00003181555,0.003733701],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5384462,"threshold_uncertainty_score":0.8595243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03161660170956798,"score_gpt":0.2882862602308763,"score_spread":0.2566696585213083,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}