{"id":"W6903491829","doi":"10.11575/prism/33397","title":"Gamma-Secretase Represents a Therapeutic Target for the Treatment of Invasive Glioma Mediated by the p75 Neurotrophin Receptor","year":2008,"lang":"en","type":"other","venue":"University of Calgary","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"York University; University of Calgary","keywords":"Low-affinity nerve growth factor receptor; Neurotrophin; Glioma; Receptor; Immunotherapy; Temozolomide","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001301025,0.0004822277,0.0007261737,0.0003176544,0.0002295663,0.000007990906,0.001059844,0.0003353961,0.002162763],"category_scores_gemma":[0.00008530538,0.0003257152,0.0005545163,0.0004367104,0.001099973,0.00005313761,0.0001103564,0.0001848032,0.0002343622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002070098,"about_ca_system_score_gemma":0.0002820471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005787458,"about_ca_topic_score_gemma":0.0005806541,"domain_scores_codex":[0.9977849,0.0004361913,0.0002683978,0.0005455689,0.0005826218,0.0003823547],"domain_scores_gemma":[0.9967058,0.0009441872,0.0008710714,0.001196891,0.0001541417,0.0001279174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001939712,0.0008315306,0.0002504581,0.00008464453,0.002277077,0.0001232155,0.00158413,0.00001056707,0.01061947,0.00005630076,0.9803534,0.001869448],"study_design_scores_gemma":[0.003775849,0.0009167508,0.0001662226,0.00007948938,0.0006535815,0.00001445015,0.000372858,0.0002534316,0.00309234,0.00002488495,0.9903277,0.0003224856],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.1669856,0.1873275,0.006338773,0.006165544,0.004476645,0.06947637,0.09567188,0.002934441,0.4606233],"genre_scores_gemma":[0.009517681,0.03408381,0.002490859,0.0003095708,0.000508054,0.00005869756,0.006942085,0.002627757,0.9434615],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.4828382,"threshold_uncertainty_score":0.9999195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02056678745422378,"score_gpt":0.2197290051021491,"score_spread":0.1991622176479254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}