{"id":"W6903491829","doi":"10.11575/prism/33397","title":"Gamma-Secretase Represents a Therapeutic Target for the Treatment of Invasive Glioma Mediated by the p75 Neurotrophin Receptor","year":2008,"lang":"en","type":"other","venue":"University of Calgary","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"York University; University of Calgary","keywords":"Low-affinity nerve growth factor receptor; Neurotrophin; Glioma; Receptor; Immunotherapy; Temozolomide","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001269366,0.0004529696,0.0003622908,0.0003790503,0.0003361481,0.0007382404,0.0005384119,0.0004573569,0.01218181],"category_scores_gemma":[0.0000956722,0.0001080849,0.0001867247,0.0003349063,0.000260731,0.0002302866,0.0002910194,0.001121884,0.003094747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001301041,"about_ca_system_score_gemma":0.001271099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007197753,"about_ca_topic_score_gemma":0.02494801,"domain_scores_codex":[0.9999369,0.000004748748,0.00000189433,0.000006094211,0.00002317806,0.00002721711],"domain_scores_gemma":[0.999952,0.000005835368,0.000005848616,0.000003954761,0.000008969191,0.00002348115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003334364,0.0009527555,0.001387435,0.001111612,0.00004793513,0.002301006,0.0002045085,0.001171855,0.468762,0.01095422,0.04651449,0.4632578],"study_design_scores_gemma":[0.001367532,0.003704977,0.01792468,0.0003133893,0.0002409085,0.003818584,0.0004524161,0.002490961,0.5111684,0.003341869,0.4551322,0.00004411323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5524294,0.1154477,0.007532704,0.009891307,0.001231868,0.0004867379,0.002081992,0.0007358128,0.3101624],"genre_scores_gemma":[0.663925,0.07988278,0.005512549,0.0009737959,0.0003075314,0.0001614429,0.001452659,0.0001025815,0.2476816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01218181,"threshold_uncertainty_score":0.04075223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02056678745422378,"score_gpt":0.2197290051021491,"score_spread":0.1991622176479254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}