{"id":"W6907654489","doi":"10.25384/sage.c.6708715","title":"Clinical Efficacy and Safety of the Intra-articular Injection of Autologous Adipose-Derived Mesenchymal Stem Cells for Knee Osteoarthritis: A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial","year":2023,"lang":"en","type":"other","venue":"Sage Journals Data","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Osteoarthritis; WOMAC; Visual analogue scale; Clinical trial; Mesenchymal stem cell; Placebo; Magnetic resonance imaging; Clinical endpoint","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0192177,0.0008977109,0.006452131,0.0007775043,0.0002378231,0.0001573768,0.001692746,0.00116628,0.001036017],"category_scores_gemma":[0.003317664,0.0006154336,0.001505404,0.0006938037,0.001120488,0.0003499955,0.0008646666,0.001374932,0.00005730989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008867219,"about_ca_system_score_gemma":0.000733237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000153065,"about_ca_topic_score_gemma":0.0007457228,"domain_scores_codex":[0.9868644,0.004460099,0.0054268,0.001243924,0.0012144,0.0007903506],"domain_scores_gemma":[0.9826546,0.006433577,0.00743196,0.002822134,0.00030157,0.0003561887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9281018,0.0009794297,0.000002293002,0.0001321119,0.006075965,0.00003628993,0.0001897473,0.00004692369,0.001591643,0.000003618844,0.01612184,0.04671839],"study_design_scores_gemma":[0.9797507,0.0022897,0.000001927328,0.004819614,0.007309164,0.0001145498,0.0001573598,0.001000538,0.0005398976,0.00003101465,0.003448498,0.0005370434],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"empirical","genre_scores_codex":[0.2188958,0.2516461,0.01639675,0.0008950513,0.03663446,0.3570017,0.1082869,0.002872302,0.007370904],"genre_scores_gemma":[0.6023874,0.1317043,0.01240108,0.0005557545,0.03335865,0.01755809,0.004402062,0.03160676,0.1660259],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.3834916,"threshold_uncertainty_score":0.9998772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06384156664091574,"score_gpt":0.3618417343000827,"score_spread":0.298000167659167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}