{"id":"W6907700092","doi":"10.25345/c57r89","title":"MassIVE MSV000088105 - Fatty Acid Synthase inhibitor TVB-3166 prevents S-palmitoylation of coronavirus Spike proteins and limits infection","year":2021,"lang":"en","type":"dataset","venue":"UC San Diego","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Coronavirus; Severe acute respiratory syndrome coronavirus; Spike (software development); Enzyme; Spike Protein; Fatty acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001037973,0.003309447,0.002642642,0.002789999,0.001069531,0.00243478,0.003185191,0.003518348,0.05019489],"category_scores_gemma":[0.005241924,0.0007579998,0.002540858,0.004008977,0.0004844188,0.0009446389,0.00151444,0.001502684,0.05045256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001538609,"about_ca_system_score_gemma":0.002566847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02677028,"about_ca_topic_score_gemma":0.05042082,"domain_scores_codex":[0.9989583,0.0001642756,0.00009193956,0.0003821964,0.0002181586,0.0001850785],"domain_scores_gemma":[0.9986053,0.0005037992,0.0001661879,0.0002730114,0.0002860565,0.0001656754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005464439,0.00005255705,0.003060137,0.00188251,0.0002368111,0.00005015976,0.00002481034,0.00112063,0.0006404701,0.0003924401,0.9875637,0.004429261],"study_design_scores_gemma":[0.002625677,0.0001823075,0.01660537,0.001165006,0.0008124551,0.0002821238,0.0001336276,0.003776615,0.002589948,0.004103377,0.9676023,0.0001212442],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0005165911,0.0003486636,0.000077219,0.000104064,0.00004018252,0.00001055543,0.9978047,0.0004305185,0.0006675448],"genre_scores_gemma":[0.001200227,0.0001365139,0.000299397,0.0001050013,0.00001001003,0.00005291282,0.9976032,0.00007269958,0.0005199949],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.05019489,"threshold_uncertainty_score":0.1679186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03005800410962518,"score_gpt":0.2940521060773421,"score_spread":0.2639941019677169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}