{"id":"W6907867474","doi":"10.25345/c5p55ds32","title":"MassIVE MSV000091012 - Persistence of targetable lesions, predicted therapy sensitivity and proteomes through disease evolution in pediatric acute lymphoblastic leukemia","year":2023,"lang":"en","type":"dataset","venue":"UC San Diego","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Persistence (discontinuity); Disease; Lymphoblastic Leukemia; Proteome; Sensitivity (control systems); Somatic evolution in cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009587758,0.001910488,0.001802388,0.002391399,0.0007477831,0.001858149,0.002376768,0.001831734,0.01693622],"category_scores_gemma":[0.004367075,0.0005552079,0.00169804,0.003339939,0.0003988487,0.0006091185,0.002189449,0.001065583,0.0140351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001275355,"about_ca_system_score_gemma":0.001914325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03310848,"about_ca_topic_score_gemma":0.0651406,"domain_scores_codex":[0.9992551,0.0001154915,0.00007019662,0.0002908401,0.0001422822,0.0001261425],"domain_scores_gemma":[0.998865,0.0003651602,0.0001615313,0.0002244537,0.0002156931,0.0001681491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008708027,0.00005487778,0.01538443,0.00173087,0.0005816967,0.0001483186,0.0000953846,0.001923096,0.001031285,0.0005938053,0.9693145,0.008271158],"study_design_scores_gemma":[0.002414188,0.0001814221,0.09832014,0.001226281,0.001212727,0.0008678135,0.0003160824,0.005180353,0.002347892,0.004215909,0.8835775,0.0001396593],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.002585487,0.0004563222,0.00009634395,0.0001362268,0.00002966936,0.000009251679,0.9956725,0.0004264597,0.0005878275],"genre_scores_gemma":[0.003262442,0.0001644797,0.0003988775,0.0000886641,0.00001161526,0.00004795763,0.9955369,0.0000671325,0.0004218559],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.03310848,"threshold_uncertainty_score":0.06583154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0189721663956892,"score_gpt":0.2520151148994724,"score_spread":0.2330429485037832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}