{"id":"W6908557647","doi":"10.3205/21dgnc413","title":"Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican","year":2021,"lang":"en","type":"article","venue":"German Medical Science (German Research Foundation)","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Glioblastoma; Gene isoform; Downregulation and upregulation; Glioma; Central nervous system; Extracellular matrix; Peptide; Extracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001858155,0.0005531193,0.0003397305,0.0001979121,0.000185054,0.000316618,0.0003548436,0.0006869727,0.001143291],"category_scores_gemma":[0.0001519384,0.0001375549,0.000318693,0.0001283562,0.0002165201,0.0002479888,0.0002519306,0.0008107542,0.0005286466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003954263,"about_ca_system_score_gemma":0.0003190071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006083373,"about_ca_topic_score_gemma":0.0006447788,"domain_scores_codex":[0.9999056,0.00001128301,0.000006116739,0.00002305397,0.00001841471,0.00003563977],"domain_scores_gemma":[0.9999388,0.000008109632,0.00001548711,0.000004755527,0.00001214917,0.0000206207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002461673,0.0001146783,0.00008093766,0.00005099482,0.00001189476,0.0001174731,0.00001158296,0.0002453173,0.9954563,0.0001553707,0.0001268377,0.003382476],"study_design_scores_gemma":[0.0006808866,0.004650112,0.003635909,0.00005257945,0.0001384533,0.00213908,0.00005574727,0.005424449,0.9678003,0.0002225841,0.01517073,0.0000291088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829466,0.003230765,0.009758311,0.0004101221,0.0002589292,0.0002482001,0.0001847496,0.0001010458,0.002861245],"genre_scores_gemma":[0.9780223,0.002836411,0.01388023,0.0006362992,0.00009175977,0.0001986719,0.0007142385,0.00003025137,0.003589924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001143291,"threshold_uncertainty_score":0.003824651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05609779613126877,"score_gpt":0.4144159938719268,"score_spread":0.3583181977406581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}