{"id":"W6908557647","doi":"10.3205/21dgnc413","title":"Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican","year":2021,"lang":"en","type":"article","venue":"German Medical Science (German Research Foundation)","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Glioblastoma; Gene isoform; Downregulation and upregulation; Glioma; Central nervous system; Extracellular matrix; Peptide; Extracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005142386,0.0002027204,0.0002778853,0.0004942993,0.000754108,0.0002186726,0.001268079,0.0001704688,0.00142894],"category_scores_gemma":[0.003304098,0.000189818,0.0001001787,0.00318137,0.001709662,0.00005590075,0.001323886,0.0005398378,0.0001411752],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002185236,"about_ca_system_score_gemma":0.003715252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001464803,"about_ca_topic_score_gemma":0.0001872495,"domain_scores_codex":[0.9933683,0.0002299503,0.0005804811,0.0009403874,0.003558175,0.001322741],"domain_scores_gemma":[0.996095,0.00009930942,0.00009999097,0.0007490695,0.00189539,0.00106121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001159163,0.0001653396,0.0002474251,0.0000478163,0.00001804955,0.00004987557,0.0001676121,0.00003821335,0.9821861,0.0009159909,0.0008225096,0.01522513],"study_design_scores_gemma":[0.00139983,0.0009054948,0.004733343,0.0003049925,0.000008660886,0.0003028602,0.0004028344,0.008747138,0.756397,0.0003350655,0.2258583,0.0006044273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843854,0.0001616522,0.01217218,0.001250584,0.00014224,0.0004792438,0.00001773212,0.00001622529,0.001374756],"genre_scores_gemma":[0.9934458,0.0001617423,0.004908256,0.0002498096,0.0004049517,0.00004429758,0.00008386227,0.00002860021,0.0006726913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2257891,"threshold_uncertainty_score":0.9994839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05609779613126877,"score_gpt":0.4144159938719268,"score_spread":0.3583181977406581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}