{"id":"W6910296362","doi":"10.48350/197919","title":"A local drug delivery system prolongs graft survival by dampening T cell infiltration and neutrophil extracellular trap formation in vascularized composite allografts.","year":2024,"lang":"en","type":"article","venue":"Bern Open Repository and Information System (University of Bern)","topic":"Organ and Tissue Transplantation Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hand and Upper Limb Clinic","funders":"","keywords":"Neutrophil extracellular traps; Infiltration (HVAC); Immunosuppression; Tacrolimus; Complement system; Toxicity; Immune system; Drug delivery; Allotransplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009638572,0.0002396706,0.0001444501,0.0001628788,0.00007090579,0.0001841126,0.0001284098,0.0001816163,0.0008159147],"category_scores_gemma":[0.00006400725,0.0000524985,0.0001602199,0.00007543019,0.0001378716,0.0001730194,0.00008535424,0.000274591,0.0001453322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001610248,"about_ca_system_score_gemma":0.00009754736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003010509,"about_ca_topic_score_gemma":0.0005028366,"domain_scores_codex":[0.999923,0.00001086808,0.00000507868,0.00002221859,0.00002012066,0.00001864342],"domain_scores_gemma":[0.9999384,0.00001140939,0.00002449477,0.000004809619,0.000005655675,0.00001537621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001273119,0.00004886346,0.000119419,0.00004401419,0.000004036999,0.00002482449,0.000006652878,0.0001448778,0.9972541,0.00002967678,0.00002950098,0.002166677],"study_design_scores_gemma":[0.0000109533,0.001315291,0.001652504,0.000004177306,0.00001928432,0.0001205199,0.000008574138,0.001047971,0.9951741,0.00001084792,0.0006324905,0.000003322242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942566,0.001911352,0.00311988,0.00002909811,0.00003826903,0.00001942389,0.00008504722,0.00006409045,0.000476375],"genre_scores_gemma":[0.997058,0.0004527709,0.001647626,0.0000170718,0.00001050685,0.00001794938,0.00007227821,0.000005973459,0.0007178991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008159147,"threshold_uncertainty_score":0.002729535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008711566842693466,"score_gpt":0.2051684462722499,"score_spread":0.1964568794295565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}