{"id":"W6910672042","doi":"10.48336/01jd-pj78","title":"Metal‐catalyzed carbenoid cascade reactions involving a C–H insertion/annulation — applications in the synthesis of carbo- and heterocycles","year":2023,"lang":"en","type":"article","venue":"Memorial University Research Repository (Memorial University)","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Annulation; Carbene; Electrophile; Carbenoid; Diazo; Cascade reaction; Pericyclic reaction; Indole test; Knoevenagel condensation; Atom economy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009501795,0.0003072377,0.0001716764,0.0001561785,0.0001792531,0.000296971,0.0002327829,0.000240877,0.002232034],"category_scores_gemma":[0.00007045138,0.0001853561,0.0002364839,0.0001544211,0.0001337188,0.0003427135,0.0002322604,0.0004901873,0.0006579436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003245089,"about_ca_system_score_gemma":0.0002387026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003252649,"about_ca_topic_score_gemma":0.0007651012,"domain_scores_codex":[0.9999418,0.000004612343,0.00000285809,0.00001574053,0.00001600164,0.00001894866],"domain_scores_gemma":[0.9999795,0.000003861407,0.000005036536,0.000002860395,0.000004348881,0.00000450193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001230442,0.000117541,0.0001837621,0.0006321068,0.00002566055,0.000306216,0.0001403489,0.001680118,0.9346867,0.01021233,0.001651855,0.05024043],"study_design_scores_gemma":[0.0000191914,0.0003536943,0.0004295763,0.00003337008,0.0000212254,0.0002831004,0.00003476733,0.002186569,0.959634,0.000669273,0.03632038,0.00001484209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.771055,0.05983824,0.0577201,0.0008997602,0.0006298074,0.0004166622,0.0005564449,0.0007819155,0.1081021],"genre_scores_gemma":[0.9246451,0.02389194,0.01955448,0.0001483028,0.00007548431,0.0001320951,0.0002289112,0.00003990864,0.03128377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002232034,"threshold_uncertainty_score":0.007466912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03122370932318283,"score_gpt":0.258098334075717,"score_spread":0.2268746247525341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}