{"id":"W6912997834","doi":"10.5683/sp3/p3xzua","title":"Replication Data for: Spy1-activated Cyclin Dependent Kinase 2 Shows Reduced Affinity for Current Synthetic Small Molecule Inhibitors of the CDK2-Cyclin Complex","year":2023,"lang":"en","type":"dataset","venue":"Borealis","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"","keywords":"Small molecule; Replication (statistics); Kinase; Current (fluid); Cyclin-dependent kinase; Cyclin A2; DNA replication","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001004157,0.002586344,0.001714957,0.001877903,0.001183246,0.001801287,0.003446985,0.002368309,0.05559347],"category_scores_gemma":[0.004013818,0.0007163775,0.002030428,0.003547471,0.000541123,0.0009558467,0.001270437,0.001863868,0.060174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001383465,"about_ca_system_score_gemma":0.002741191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02209011,"about_ca_topic_score_gemma":0.04720503,"domain_scores_codex":[0.9990641,0.0001234993,0.0001038696,0.0003589025,0.0002190189,0.0001306057],"domain_scores_gemma":[0.9980065,0.0005354829,0.0001817662,0.0006634737,0.0004101847,0.0002024955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003894809,0.0000662955,0.001558797,0.001344302,0.00008733656,0.00005738902,0.00002983059,0.0008500703,0.001343766,0.0005347091,0.9910982,0.002639841],"study_design_scores_gemma":[0.001212437,0.00009675584,0.01004632,0.0002730875,0.0001639515,0.0002171909,0.0001037586,0.001736599,0.004227089,0.002195684,0.9796401,0.00008712914],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0003463003,0.00006044219,0.00006730921,0.00005204975,0.0000280163,0.000009103286,0.9984994,0.0004273598,0.0005100482],"genre_scores_gemma":[0.000713725,0.00003018711,0.0002408087,0.00002602126,0.000003626838,0.00003164297,0.9986258,0.00005591603,0.0002722585],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.05559347,"threshold_uncertainty_score":0.1859787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1522697361149664,"score_gpt":0.3646377311167949,"score_spread":0.2123679950018285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}