{"id":"W6920499570","doi":"10.60692/7n84h-dy657","title":"Mucosal Healing and Clinical Efficacy of Adalimumab in Small Intestinal Crohn's Disease (SIMCHA Study): Final Results From a Prospective, Open-Label, Single-Arm Study","year":2023,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Adalimumab; Calprotectin; Capsule endoscopy; Crohn's disease; Endoscopy; Clinical efficacy; Colonoscopy; Inflammatory bowel disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006689609,0.0009542038,0.001560491,0.0004105929,0.0003568412,0.0008691757,0.000479007,0.0009205206,0.00130573],"category_scores_gemma":[0.002268307,0.0003969565,0.001492724,0.0004066268,0.0007683581,0.0006662476,0.0004480281,0.001130151,0.0003572328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003267605,"about_ca_system_score_gemma":0.0005490431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003025851,"about_ca_topic_score_gemma":0.0005386916,"domain_scores_codex":[0.9983103,0.001156984,0.0001063452,0.0001224553,0.0001929414,0.0001109045],"domain_scores_gemma":[0.9974758,0.0006687918,0.0007479277,0.0002802656,0.0002147104,0.0006124482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7819702,0.02337396,0.1196674,0.0009011865,0.004736648,0.0002465112,0.0003695863,0.0005498228,0.01659925,0.0001165123,0.0007625227,0.05070641],"study_design_scores_gemma":[0.2666719,0.3909514,0.3337744,0.0001037089,0.002813785,0.0004047299,0.0001411648,0.0009694625,0.002378613,0.0001366491,0.001603247,0.0000509501],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963158,0.002112402,0.0002168567,0.00005357872,0.00002327983,0.000449956,0.000279559,0.00001571531,0.0005327655],"genre_scores_gemma":[0.9964597,0.001014732,0.0005524763,0.0001822981,0.0001263743,0.0004396608,0.0006920138,0.000006936702,0.000525694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006689609,"threshold_uncertainty_score":0.03537846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0896358178188472,"score_gpt":0.3065298539851788,"score_spread":0.2168940361663316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}