{"id":"W6920610762","doi":"10.60692/w0xq0-yat25","title":"Foot-and-Mouth Disease: Optimization, Reproducibility, and Scalability of High-Yield Production of Virus-Like Particles for a Next-Generation Vaccine","year":2020,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Animal Disease Management and Epidemiology","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Immunogenicity; Transferability; Biosafety; Scalability; Production (economics); Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003071669,0.0006787947,0.0004612925,0.0005261176,0.0003323054,0.0008977071,0.0004903441,0.0005643013,0.0006587718],"category_scores_gemma":[0.001837498,0.0002900364,0.0004259743,0.0004810869,0.0002971412,0.000466506,0.0004637142,0.0005944284,0.000451766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006471642,"about_ca_system_score_gemma":0.0005289846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001257326,"about_ca_topic_score_gemma":0.001648065,"domain_scores_codex":[0.9975139,0.0006237435,0.0003376377,0.0003489134,0.001018917,0.0001568697],"domain_scores_gemma":[0.9993344,0.0001983558,0.0001221196,0.0001194077,0.0001896197,0.00003603423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000397801,0.00007105447,0.0004237155,0.00004946074,0.000007227015,0.00002723106,0.00004120082,0.0006470842,0.9961709,0.00006453063,0.00003906504,0.002418655],"study_design_scores_gemma":[0.00001233718,0.0002597328,0.002241937,0.000007639316,0.00001980473,0.00007870934,0.0000197965,0.002542103,0.9934425,0.00003714284,0.001326692,0.00001158396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9067177,0.001837624,0.0864485,0.0002424235,0.00007584627,0.0009686505,0.0008097316,0.0003619631,0.00253748],"genre_scores_gemma":[0.8652486,0.001513401,0.1263858,0.00007638863,0.0000269521,0.0008016516,0.00270878,0.0002067093,0.003031736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003071669,"threshold_uncertainty_score":0.01624471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1083606059355783,"score_gpt":0.2277539558282458,"score_spread":0.1193933498926675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}