{"id":"W6920722622","doi":"10.6084/m9.figshare.19101935.v1","title":"Additional file 1 of Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery","year":2022,"lang":"en","type":"article","venue":"Figshare","topic":"Hemodynamic Monitoring and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Kingston General Hospital; Population Health Research Institute; Université de Montréal; Western University; London Health Sciences Centre; McMaster University","funders":"","keywords":"Tranexamic acid; Randomized controlled trial; Perioperative; Clinical trial; MEDLINE","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.01024294,0.001519523,0.002733772,0.001725546,0.001065327,0.002008407,0.001655103,0.002128835,0.812507],"category_scores_gemma":[0.1055567,0.001229815,0.001795189,0.002842384,0.0006285842,0.002065279,0.0008460895,0.001958862,0.08377165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00144586,"about_ca_system_score_gemma":0.003953781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002149585,"about_ca_topic_score_gemma":0.004681718,"domain_scores_codex":[0.9950743,0.002487159,0.000897618,0.0005549829,0.0006177239,0.0003682191],"domain_scores_gemma":[0.9181114,0.06458396,0.006452455,0.00317653,0.006003295,0.001672303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.01297409,0.0005605335,0.00115496,0.0192481,0.0004357528,0.00008072233,0.0001152412,0.0006421579,0.0001439549,0.00455224,0.9419056,0.01818675],"study_design_scores_gemma":[0.3632777,0.004181173,0.01329651,0.02180435,0.001354781,0.0004313273,0.0002695604,0.003443545,0.0008941921,0.0302243,0.5605575,0.0002650198],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"protocol","genre_scores_codex":[0.001071865,0.0003766125,0.00219228,0.001964186,0.0005276988,0.02905029,0.953688,0.0006477375,0.01048142],"genre_scores_gemma":[0.0376119,0.001445201,0.0295612,0.01010897,0.001679481,0.5456079,0.3059187,0.00136895,0.06669772],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.812507,"threshold_uncertainty_score":0.2674361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07352987794960031,"score_gpt":0.3051729970652907,"score_spread":0.2316431191156904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}