{"id":"W6920788676","doi":"10.6084/m9.figshare.26630107.v1","title":"Additional file 2 of Autoimmune PaneLs as PrEdictors of Toxicity in Patients TReated with Immune Checkpoint InhibiTors (ALERT)","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto General Hospital; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Toxicity; Immunotherapy; Pembrolizumab; Immune system; Immune checkpoint; Ipilimumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001153765,0.000961675,0.001338938,0.001975428,0.0006088165,0.001441807,0.001308029,0.00112199,0.8616844],"category_scores_gemma":[0.03676035,0.0004515925,0.00125091,0.002927609,0.0001739391,0.001639249,0.0008483871,0.0008542613,0.1260451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008004961,"about_ca_system_score_gemma":0.001208383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006213184,"about_ca_topic_score_gemma":0.008834114,"domain_scores_codex":[0.9991966,0.0001586688,0.0001904458,0.0001933658,0.000141204,0.000119771],"domain_scores_gemma":[0.9712769,0.02251111,0.001896825,0.001039464,0.002735967,0.0005397598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006887582,0.00008706182,0.006398679,0.003437456,0.00009807949,0.0001006634,0.00004679224,0.0003489429,0.00007851883,0.0004614746,0.9767086,0.01154507],"study_design_scores_gemma":[0.01341416,0.0007364334,0.1383268,0.01221803,0.0009493263,0.002298666,0.0007635344,0.004537768,0.001404505,0.0208964,0.8041373,0.0003169986],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0004035457,0.00004265762,0.0001821339,0.0001448176,0.00002996788,0.00007700841,0.9978175,0.0001765179,0.001125894],"genre_scores_gemma":[0.02520728,0.0003389659,0.003500318,0.001412174,0.0003618239,0.002465555,0.9478219,0.0009700586,0.01792199],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.8616844,"threshold_uncertainty_score":0.1972905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01301244328696985,"score_gpt":0.2282902159117537,"score_spread":0.2152777726247838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}