{"id":"W6920953531","doi":"10.6084/m9.figshare.12762386","title":"Satralizumab: First Approval","year":2020,"lang":"en","type":"other","venue":"Figshare","topic":"Multiferroics and related materials","field":"Materials Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Clinical trial; Drug approval; Neuromyelitis optica; Drug development; Informed consent; Authorization; Marketing authorization","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00002619006,0.0002981808,0.000375383,0.00006406056,0.00005820502,0.0001400777,0.0004636672,0.0005029553,0.9526767],"category_scores_gemma":[0.0001864474,0.0002464814,0.0001014284,0.00007524787,0.00001028288,0.00002958214,0.0002077695,0.0001533188,0.1068735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002192793,"about_ca_system_score_gemma":0.00006187034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006982677,"about_ca_topic_score_gemma":0.0000378966,"domain_scores_codex":[0.9987466,0.0000308516,0.0002174487,0.0004709811,0.0002390638,0.0002950335],"domain_scores_gemma":[0.9992259,0.00002424954,0.0002316902,0.0003562234,0.00001716461,0.0001447629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000430414,0.00001089612,8.798101e-8,0.0006788996,0.00001265516,0.0000453905,0.00003111585,0.000002023887,0.001889925,0.00001705034,0.9972318,0.00007582484],"study_design_scores_gemma":[0.0001761432,0.00001875936,0.000002884261,0.002248106,0.00001373832,0.000006714168,0.00000284261,0.00001695162,0.004222337,0.00001066518,0.9929525,0.0003283224],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.000002861563,0.0007603129,5.119199e-7,0.0001142851,0.0007065466,0.0003866283,0.4672474,0.0006221515,0.5301594],"genre_scores_gemma":[0.0003699618,0.00006797479,0.0009779263,0.0004430103,0.003145085,0.0003667926,0.2416411,0.001359342,0.7516288],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.8458032,"threshold_uncertainty_score":0.9999987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03839813055143639,"score_gpt":0.2478528183167939,"score_spread":0.2094546877653575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}