{"id":"W6921001074","doi":"10.6084/m9.figshare.26627293","title":"Additional file 3 of Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation","year":2024,"lang":"en","type":"dataset","venue":"DIGITAL.CSIC (Spanish National Research Council (CSIC))","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Embryonic stem cell; Vitamin C; Demethylation; Stem cell; Methylation; DNA methylation; DNA demethylation; Demethylase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","scholarly_communication","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.0112095,0.001388654,0.001418262,0.003350508,0.0004241906,0.00158987,0.002494515,0.001173262,0.2639489],"category_scores_gemma":[0.04605202,0.001532207,0.0006081437,0.005025262,0.0009612901,0.003007567,0.001520343,0.003914386,0.05929079],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.02929869,"about_ca_system_score_gemma":0.03353731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003387968,"about_ca_topic_score_gemma":0.002971672,"domain_scores_codex":[0.9531963,0.0008307049,0.002508533,0.002569671,0.0387034,0.0021914],"domain_scores_gemma":[0.9517245,0.01516014,0.001250802,0.001420715,0.02973797,0.0007058691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003538232,0.001434863,0.000004602072,0.0008364093,0.0006269976,0.0001225267,0.00005908498,0.000188123,0.001469492,0.00006570749,0.9938014,0.001036955],"study_design_scores_gemma":[0.00112669,0.0003899421,0.00006919511,0.001562866,0.00005214608,0.00002238503,0.0001868384,0.001426159,0.001082308,0.001830201,0.9910585,0.001192731],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0001930194,0.0002308571,0.00000591796,0.00007799028,0.0003729616,0.002180855,0.9890003,0.0002070354,0.00773112],"genre_scores_gemma":[0.001055871,0.000135432,0.0001735085,0.00006344944,0.0008520457,0.003256871,0.9770978,0.0004198281,0.01694516],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.2046581,"threshold_uncertainty_score":0.9998864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09974961810807188,"score_gpt":0.3314548974137835,"score_spread":0.2317052793057116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}