{"id":"W6921144045","doi":"10.6084/m9.figshare.28924817.v1","title":"Additional file 3 of IL-6-mediated tumorigenicity and antioxidant state in squamous cell carcinoma cells are driven by CD109 via stabilization of IL-6 receptor-alpha and activation of STAT3/NRF2 pathway","year":2025,"lang":"en","type":"article","venue":"Figshare","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital; McGill University","funders":"","keywords":"Antioxidant; Basal cell; Cell culture; Cell; Apoptosis; Cell growth; Cell survival; DNA damage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001183112,0.001476272,0.001982231,0.002230689,0.00106636,0.001946034,0.002067028,0.001575547,0.8997121],"category_scores_gemma":[0.01081663,0.0009184154,0.001094331,0.003789198,0.0003281113,0.001658173,0.001197727,0.001147995,0.2886601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00108207,"about_ca_system_score_gemma":0.0015077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004606541,"about_ca_topic_score_gemma":0.00818126,"domain_scores_codex":[0.9994565,0.00005996277,0.00009161019,0.000148205,0.0001513391,0.00009244068],"domain_scores_gemma":[0.9918666,0.005913658,0.0004111486,0.0005379204,0.0009380112,0.0003326139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007071372,0.0002134396,0.001921268,0.005050834,0.00008042849,0.0002037092,0.0001007311,0.0006857162,0.001300679,0.0011614,0.9767815,0.0117932],"study_design_scores_gemma":[0.005063676,0.0005022016,0.02443732,0.002736316,0.000199793,0.0007571181,0.0003852232,0.002443669,0.004608458,0.01340763,0.9452175,0.0002410573],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0001571319,0.00001675903,0.0003107879,0.00005306716,0.00002626872,0.0000399944,0.9979917,0.0006706769,0.0007336942],"genre_scores_gemma":[0.004032898,0.0001033728,0.002781449,0.0002373017,0.00004198463,0.0006468977,0.9852864,0.001351066,0.005518652],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.8997121,"threshold_uncertainty_score":0.1430485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006069174020886431,"score_gpt":0.1949510603952318,"score_spread":0.1888818863743454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}