{"id":"W6921155882","doi":"10.6084/m9.figshare.27894344.v1","title":"Additional file 5 of Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities","year":2024,"lang":"en","type":"other","venue":"Figshare","topic":"History of Computing Technologies","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pancreas Centre (Canada); BC Cancer Agency; Dalhousie University; Canada's Michael Smith Genome Sciences Centre; Vancouver Coastal Health Research Institute; University of British Columbia","funders":"","keywords":"In silico; Histone; Gene; Cancer; Epigenetics; Suppressor; Gene expression; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00002872345,0.0001605152,0.0002265924,0.0001675918,0.00003791883,0.00002853752,0.0006310446,0.0001883892,0.6779776],"category_scores_gemma":[0.0006431386,0.0001443234,0.00007701837,0.0003417836,0.00002706911,0.00004179488,0.0006511864,0.000225347,0.00008463032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001563925,"about_ca_system_score_gemma":0.0002323175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008994036,"about_ca_topic_score_gemma":0.0002653252,"domain_scores_codex":[0.9989581,0.00002975203,0.0002333118,0.0003380295,0.0002736612,0.0001671221],"domain_scores_gemma":[0.9987006,0.0005862037,0.0002514216,0.0003545598,0.0000823271,0.00002485841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[2.729074e-7,0.00001751465,0.000003154077,0.0001257454,0.00001533575,5.960546e-7,0.00007251432,0.002608088,0.00002552823,0.00001941103,0.9968041,0.000307745],"study_design_scores_gemma":[0.0000610203,0.00001100166,0.004365726,0.00328344,0.000004044242,0.000001567725,0.00001130142,0.005314788,0.00007193757,0.0001062424,0.986604,0.0001648977],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"other","genre_scores_codex":[0.000003427912,0.001714749,0.0001931362,0.00007987618,0.0001948698,0.0002167006,0.9877407,0.0001234004,0.009733152],"genre_scores_gemma":[0.002180701,0.00002225698,0.06747761,0.0005480684,0.001260578,0.004288841,0.4205424,0.0005036254,0.5031759],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.677893,"threshold_uncertainty_score":0.5885336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02495930282120264,"score_gpt":0.2133559423053603,"score_spread":0.1883966394841577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}