{"id":"W6922016904","doi":"10.11575/prism/49405","title":"Universal Lynch Syndrome Screening in Newly Diagnosed Colorectal Cancer: Impact of an Alberta-wide Screening Program","year":2025,"lang":"en","type":"other","venue":"Open MIND","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Lynch syndrome; Genetic testing; Germline mutation; Germline; Medical genetics; Colorectal cancer; Cancer; Odds ratio; Hereditary Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002513127,0.000240678,0.000259563,0.0005728094,0.0008636535,0.001261784,0.001099811,0.0003591,0.001867246],"category_scores_gemma":[0.009739819,0.0001589148,0.0005156347,0.001022785,0.0005069485,0.000329945,0.001685298,0.0008105101,0.0001193178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01787836,"about_ca_system_score_gemma":0.05991993,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9161102,"about_ca_topic_score_gemma":0.952878,"domain_scores_codex":[0.9972339,0.0008183487,0.00007382708,0.000137052,0.0009476281,0.0007892339],"domain_scores_gemma":[0.9924038,0.001435631,0.0007252857,0.0002542124,0.00182789,0.003353113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00153181,0.0010004,0.776292,0.0008682667,0.0003175573,0.0005313131,0.001638591,0.003510409,0.001373714,0.001240788,0.01092137,0.2007738],"study_design_scores_gemma":[0.0001619964,0.0009675586,0.9876067,0.0003693174,0.0002244572,0.0001878706,0.001908338,0.001369186,0.0003576787,0.00018564,0.006635373,0.00002587068],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9703829,0.002683551,0.0004485254,0.008621628,0.0001389691,0.0003357428,0.001833555,0.0001139278,0.01544126],"genre_scores_gemma":[0.9931574,0.001334087,0.001251976,0.001117486,0.00004093181,0.00006181833,0.0008464614,0.00001222305,0.002177628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08388984,"threshold_uncertainty_score":0.1687678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02347784760228308,"score_gpt":0.3419502869116601,"score_spread":0.3184724393093771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}