{"id":"W6922109673","doi":"10.1021/acsinfecdis.1c00278.s001","title":"Antiviral Potential of the Antimicrobial Drug Atovaquone\\nagainst SARS-CoV‑2 and Emerging Variants of Concern","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Atovaquone; Drug; Antiviral drug; Viral replication; Malaria; Virus; Antimicrobial; Proguanil","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000041793,0.00009503154,0.0001399681,0.000009796481,0.00004768829,0.000009384001,0.000137276,0.00008266349,0.00107277],"category_scores_gemma":[0.0001925822,0.00007337607,0.00009523363,0.00007759938,0.00002196769,0.000003920626,0.0003299709,0.0000695062,0.000006389298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003232184,"about_ca_system_score_gemma":0.00006190449,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004098507,"about_ca_topic_score_gemma":0.000004046688,"domain_scores_codex":[0.9993691,0.00007043417,0.0001354106,0.0001981358,0.00008498351,0.0001419358],"domain_scores_gemma":[0.9996306,0.00001126949,0.000101541,0.0001440584,0.00009117659,0.00002140469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002115426,0.00003265342,0.00003452169,0.00008265785,0.0000313001,0.000007246052,0.0000166978,0.000007276028,0.9719511,0.000006638565,0.02682075,0.0009880663],"study_design_scores_gemma":[0.0004089219,0.00003234584,0.001103354,0.000175575,0.00001341962,0.000008511662,0.00001160669,0.00009535626,0.991914,0.00001152451,0.006139397,0.00008601264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855356,0.0002814824,0.000009797805,0.00005566178,0.0001434325,0.0001103114,0.01346018,0.000004270677,0.0003993137],"genre_scores_gemma":[0.9966902,0.00003120536,0.00006419219,0.0002710292,0.00008127028,0.000005216474,0.002781839,0.000009510019,0.00006560855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02068135,"threshold_uncertainty_score":0.9998404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01929261781519124,"score_gpt":0.2723851435573524,"score_spread":0.2530925257421612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}