{"id":"W6922109673","doi":"10.1021/acsinfecdis.1c00278.s001","title":"Antiviral Potential of the Antimicrobial Drug Atovaquone\\nagainst SARS-CoV‑2 and Emerging Variants of Concern","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Atovaquone; Drug; Antiviral drug; Viral replication; Malaria; Virus; Antimicrobial; Proguanil","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001814615,0.000269188,0.0001997569,0.0001424909,0.0001791738,0.0004228518,0.0001848103,0.0002294426,0.001929006],"category_scores_gemma":[0.00008986134,0.00007786776,0.0002722257,0.00009743422,0.0001542276,0.0001785651,0.0001085143,0.000422055,0.0003457692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003714625,"about_ca_system_score_gemma":0.0002799741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001602508,"about_ca_topic_score_gemma":0.004356488,"domain_scores_codex":[0.999877,0.00003036949,0.00001042367,0.00001737345,0.00003255611,0.00003231629],"domain_scores_gemma":[0.999954,0.00001093341,0.0000082355,0.000007125424,0.00001092592,0.000008788493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002159274,0.0000873656,0.0005502172,0.00009963106,0.0000107916,0.00007919153,0.00002695919,0.0002216508,0.9945509,0.00025688,0.00009186912,0.003808739],"study_design_scores_gemma":[0.00004992845,0.003550564,0.006611333,0.00002560257,0.00003086028,0.0004978854,0.00009229517,0.001110057,0.9815145,0.00008341801,0.006423104,0.00001035105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863418,0.006440972,0.001127162,0.0001886752,0.00005830665,0.00003954567,0.0006677996,0.00003179809,0.005103996],"genre_scores_gemma":[0.9931211,0.002591545,0.0009559813,0.00005961724,0.00001021379,0.00001617685,0.0004898422,0.000003578273,0.002752029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001929006,"threshold_uncertainty_score":0.006453216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01929261781519124,"score_gpt":0.2723851435573524,"score_spread":0.2530925257421612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}