{"id":"W6922179439","doi":"10.1021/jo900950x.s001","title":"An Improved Synthesis of Pyridine−Thiazole Cores of Thiopeptide Antibiotics","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Medieval European History and Architecture","field":"Arts and Humanities","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Antibiotics; Pyridine; Core (optical fiber); Key (lock); Depsipeptide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005090066,0.0001044171,0.0001831062,0.00004306469,0.0000700969,0.0000114924,0.0002443125,0.00002879946,0.1442874],"category_scores_gemma":[0.0005559137,0.00006411145,0.00007620221,0.00001718001,0.00006593769,0.0001052481,0.00004110656,0.00005633102,0.0002499769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006980717,"about_ca_system_score_gemma":0.0000280112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000648608,"about_ca_topic_score_gemma":0.0000416578,"domain_scores_codex":[0.9993665,0.00004851312,0.0002080117,0.0001361402,0.0001151641,0.0001256789],"domain_scores_gemma":[0.9992029,0.0001805417,0.0001661274,0.0002728899,0.0001204837,0.00005702458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003967887,0.0006343212,0.0002039936,0.003322667,0.0002100431,0.00003969773,0.0305842,0.00003408178,0.2834197,0.01565155,0.595798,0.069705],"study_design_scores_gemma":[0.0003065856,0.0003303007,0.0006979973,0.003335205,0.0000320405,0.000002108305,0.0004182757,0.00008476905,0.2612238,0.00009628773,0.7331898,0.0002828103],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.2456568,0.0004736785,0.000003366897,0.0002018235,0.0004839051,0.0005047238,0.5694266,0.0002298585,0.1830192],"genre_scores_gemma":[0.9972162,0.000003791622,0.00003139903,0.00005897516,0.0002606469,0.000001633922,0.0008916424,0.00002132527,0.001514374],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.7515594,"threshold_uncertainty_score":0.8564948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03401462203632086,"score_gpt":0.2209434227107212,"score_spread":0.1869288006744003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}