{"id":"W6926192565","doi":"10.24433/co.8764089.v4","title":"Accessibility Over Transposable Elements Reveals Genetic Determinants of Stemness Properties in Normal and Leukemic Hematopoiesis v2","year":2025,"lang":"en","type":"other","venue":"Code Ocean","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Chromatin; Myeloid leukemia; Stem cell; Haematopoiesis; Transposable element; RUNX1; Leukemia; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001019607,0.0001035978,0.00009209342,0.0004578348,0.00006553772,0.0002351334,0.00006479338,0.000112494,0.0007752],"category_scores_gemma":[0.0002236284,0.00006041225,0.00007874329,0.0002087065,0.0001134559,0.00005586202,0.0001557518,0.0001203796,0.0001363392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008331876,"about_ca_system_score_gemma":0.00005497618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005317552,"about_ca_topic_score_gemma":0.0007424626,"domain_scores_codex":[0.9999381,0.000008859122,0.000004830837,0.00001599441,0.0000181584,0.00001397996],"domain_scores_gemma":[0.9999084,0.00002830635,0.00002258768,0.000007394531,0.00001120256,0.00002214469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001880792,0.00001659042,0.02628982,0.00001190216,0.000007500586,0.00004714102,0.00005458711,0.0001700305,0.9689192,0.00007847885,0.00001382725,0.004202828],"study_design_scores_gemma":[0.00001455032,0.000732889,0.5958593,0.000006096921,0.0000337626,0.001186363,0.0002019427,0.005767924,0.3947905,0.0002348769,0.001159665,0.00001208005],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"software","genre_scores_codex":[0.9989924,0.00006609947,0.0006692279,0.000003705739,5.631842e-7,0.000003636768,0.0000723781,0.000007122816,0.0001848252],"genre_scores_gemma":[0.9990019,0.00004904138,0.0004595252,0.000003894463,0.000001058564,0.000003286536,0.0002356111,0.000003658967,0.0002419814],"genre_candidate":"software","genre_consensus":null,"teacher_disagreement_score":0.0007752,"threshold_uncertainty_score":0.002593279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01789834651795584,"score_gpt":0.2661002207916072,"score_spread":0.2482018742736513,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}