{"id":"W6927542855","doi":"10.3389/fnins.2024.1375299.s002","title":"Data_Sheet_2_Proteomics and lipidomic analysis reveal dysregulated pathways associated with loss of sacsin.docx","year":2024,"lang":"en","type":"dataset","venue":"Figshare","topic":"Microbial Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Proteomics; Ataxia; Homeostasis; Unfolded protein response; Protein aggregation; Cytoskeleton; Lipid metabolism; Proteome","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002138631,0.003091493,0.003778403,0.006770344,0.002503399,0.004241692,0.003781676,0.003287388,0.607198],"category_scores_gemma":[0.006240467,0.001778938,0.002894626,0.006738128,0.001174736,0.004303853,0.00220655,0.004524828,0.1440942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00211748,"about_ca_system_score_gemma":0.005620977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008652027,"about_ca_topic_score_gemma":0.01354624,"domain_scores_codex":[0.9980273,0.0001259208,0.0002575589,0.0003743974,0.0007220836,0.0004927184],"domain_scores_gemma":[0.9940113,0.002385186,0.0007032068,0.0007193084,0.001370215,0.0008107882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001118343,0.0003072284,0.00465331,0.01262516,0.0002849175,0.0007054218,0.0002569071,0.0008581147,0.01269291,0.003289672,0.9542161,0.008991975],"study_design_scores_gemma":[0.003039895,0.0004054719,0.04448482,0.003618792,0.0002373122,0.001311131,0.0007362572,0.002405047,0.01550043,0.009128709,0.9186902,0.0004418603],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0005133252,0.00007747063,0.0005361154,0.0002346482,0.0001584404,0.0001455536,0.994481,0.002108285,0.001745285],"genre_scores_gemma":[0.005021213,0.0005135135,0.007588293,0.00167099,0.0001338406,0.001906315,0.974216,0.001801632,0.007148104],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.607198,"threshold_uncertainty_score":0.5602844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01285066792069738,"score_gpt":0.2351299248290486,"score_spread":0.2222792569083512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}