{"id":"W6929210521","doi":"10.48350/197634","title":"Transcriptome profiling of immune rejection mechanisms in a porcine vascularized composite allotransplantation model.","year":2024,"lang":"en","type":"article","venue":"Open Access CRIS of the University of Bern","topic":"Organ and Tissue Transplantation Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hand and Upper Limb Clinic","funders":"","keywords":"Immune system; Transcriptome; Allotransplantation; Downregulation and upregulation; Gene expression profiling; Transplant rejection; KEGG; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001970024,0.0002339568,0.0004058047,0.000621649,0.0002723656,0.0004434068,0.0001412837,0.0002444105,0.0005965766],"category_scores_gemma":[0.0001212208,0.0001173509,0.0004463601,0.0006143826,0.0002006166,0.000210975,0.0002308252,0.0004489119,0.0002161332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001667183,"about_ca_system_score_gemma":0.0002928455,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004172315,"about_ca_topic_score_gemma":0.0006922919,"domain_scores_codex":[0.9998249,0.00001412627,0.000009477527,0.00006898195,0.00004534707,0.00003716357],"domain_scores_gemma":[0.9998989,0.00001652126,0.000028989,0.000007969253,0.00002603756,0.00002168947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002348525,0.00003952824,0.004101793,0.0002079093,0.0000285325,0.0001351472,0.00008444514,0.0001871485,0.9894034,0.00007552501,0.0001413719,0.005360444],"study_design_scores_gemma":[0.00004502777,0.002298071,0.4641545,0.0001689003,0.0005519362,0.002467375,0.001048516,0.01054557,0.5024889,0.0007154502,0.01542573,0.00009009157],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9707509,0.005099907,0.01461186,0.00009058908,0.00007157812,0.0001374079,0.006734617,0.000163959,0.002339132],"genre_scores_gemma":[0.967585,0.003715876,0.01435903,0.0002316697,0.00003263779,0.0004570092,0.01059348,0.00004957413,0.002975648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000621649,"threshold_uncertainty_score":0.001995742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04363665388442652,"score_gpt":0.3398557126838377,"score_spread":0.2962190587994112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}