{"id":"W6929796655","doi":"10.5167/uzh-38680","title":"Metabolic profiling of hearts exposed to sevoflurane and propofol reveals distinct regulation of fatty acid and glucose oxidation: CD36 and pyruvate dehydrogenase as key regulators in anesthetic-induced fuel shift","year":2010,"lang":"en","type":"article","venue":"Open MIND","topic":"Advanced Differential Geometry Research","field":"Physics and Astronomy","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"CD36; Propofol; Fatty acid; Glucose transporter; Metabolism; Oxidative phosphorylation; Glycolysis; Sevoflurane","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004303664,0.000166509,0.0003842339,0.0001587064,0.00006531667,0.00007628824,0.0001348172,0.00005750948,0.0002058527],"category_scores_gemma":[0.00005493532,0.0001521505,0.00002447189,0.000325719,0.0001104102,0.0003097134,0.0002161215,0.0001455675,0.00000352188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005294624,"about_ca_system_score_gemma":0.00005188552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001024951,"about_ca_topic_score_gemma":0.00006403879,"domain_scores_codex":[0.9987172,0.00008465537,0.0003837945,0.0003870399,0.00020663,0.0002206554],"domain_scores_gemma":[0.9992228,0.00005442167,0.0001722152,0.0002951604,0.00008831466,0.0001671497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001475462,0.00008155955,0.08083944,0.00003919161,0.00001740444,0.000001269709,0.0006066005,0.000004722537,0.8852158,0.0006789102,2.822447e-7,0.03236729],"study_design_scores_gemma":[0.0008824414,0.00009725463,0.1474552,0.00004857661,0.00001804822,0.000002915343,0.0001526642,0.0001183647,0.8495197,0.001518016,0.00005139889,0.000135466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982315,0.00006982052,0.0001327878,0.00008583297,0.00001916816,0.001257992,0.00003792391,0.000001387013,0.0001635736],"genre_scores_gemma":[0.9935006,0.000002245562,0.00630347,0.000002370207,0.00002688099,0.00003619793,0.0000457259,0.00001667767,0.00006582143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06661574,"threshold_uncertainty_score":0.6204519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02353986156011392,"score_gpt":0.3083433292824642,"score_spread":0.2848034677223503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}