{"id":"W6931258154","doi":"10.5281/zenodo.3686310","title":"CRISPR-mediated introduction of single nucleotide changes in iPSCs","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Forensic and Genetic Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Induced pluripotent stem cell; Nucleotide; Genome; Human genome; Protocol (science); HEK 293 cells","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008874299,0.0006860766,0.0006632326,0.0007869079,0.0006460524,0.0007773127,0.001222321,0.0009023116,0.00703729],"category_scores_gemma":[0.0006293923,0.0007055484,0.0007844914,0.0004195969,0.0004919551,0.0003749507,0.0009729035,0.00230214,0.004932847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004706671,"about_ca_system_score_gemma":0.0007412487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006097238,"about_ca_topic_score_gemma":0.001024765,"domain_scores_codex":[0.9990846,0.000116104,0.0001460468,0.0002014312,0.000325151,0.0001266854],"domain_scores_gemma":[0.9996004,0.00009701604,0.00004605514,0.000150585,0.00005196719,0.00005414607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009693111,0.00005786354,0.000141019,0.0002357816,0.00001880682,0.0003498052,0.0001082092,0.0006812308,0.9769138,0.004222062,0.002529379,0.01464527],"study_design_scores_gemma":[0.00003317277,0.00007237691,0.0006276065,0.00005002107,0.00003262498,0.0006339973,0.0000257009,0.001467365,0.9218905,0.000571989,0.0745638,0.00003080727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1978518,0.003508582,0.7046525,0.0007455602,0.001660999,0.006427371,0.02726777,0.0141203,0.04376503],"genre_scores_gemma":[0.4372978,0.004788606,0.4416569,0.0008887889,0.0001336413,0.008803189,0.03571106,0.003449369,0.06727064],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00703729,"threshold_uncertainty_score":0.02354205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02908958235286585,"score_gpt":0.2407999946639975,"score_spread":0.2117104123111316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}