{"id":"W6939349684","doi":"10.60692/ph6mz-d1132","title":"Characterization of CYP2B6 and CYP2A6 Pharmacogenetic Variation in Sub‐Saharan African Populations","year":2023,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Manitoba","funders":"","keywords":"1000 Genomes Project; Allele; Pharmacogenetics; Allele frequency; CYP2A6; Genetic variation; Genome; Human genetic variation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006010658,0.0002420634,0.0003641362,0.0008805128,0.000370358,0.0004684471,0.000180185,0.0002465204,0.00252228],"category_scores_gemma":[0.001780333,0.0001339419,0.000462284,0.001862674,0.0001885602,0.0002253863,0.000379475,0.0003192024,0.0003075706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001241999,"about_ca_system_score_gemma":0.0001605983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002590659,"about_ca_topic_score_gemma":0.003341031,"domain_scores_codex":[0.9996123,0.0001238741,0.00003994577,0.0001275615,0.00005512302,0.00004127771],"domain_scores_gemma":[0.9996396,0.0001243302,0.0001253223,0.00004385005,0.00003883943,0.00002799015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009255451,0.00004954093,0.9219258,0.0002601278,0.0007047977,0.0008445736,0.001351255,0.001607048,0.01402899,0.0007599609,0.002629506,0.0549128],"study_design_scores_gemma":[0.00005969057,0.00008042025,0.9807379,0.00008925342,0.0002567224,0.001653905,0.0005900852,0.002855482,0.00183696,0.0007937754,0.01102681,0.00001905983],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914677,0.001351439,0.001790604,0.0001240166,0.000008860778,0.00001713268,0.00451837,0.00002974519,0.0006921566],"genre_scores_gemma":[0.9904856,0.00101726,0.002642523,0.00007720649,0.00001794046,0.0000358371,0.005408076,0.00003417031,0.0002813247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002590659,"threshold_uncertainty_score":0.008437872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1296194672235067,"score_gpt":0.3467793525055919,"score_spread":0.2171598852820852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}