{"id":"W6939438112","doi":"10.6084/m9.figshare.12737315","title":"Additional file 1 of LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes","year":2020,"lang":"en","type":"article","venue":"Open MIND","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"PVT1; Autophagy; Pancreatic cancer; Gemcitabine; Transcription factor; Transcription (linguistics); Cell culture","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00118112,0.001170798,0.001549476,0.001684081,0.001022939,0.001657864,0.001564929,0.001342855,0.8899521],"category_scores_gemma":[0.01633738,0.0007097052,0.001017795,0.002758209,0.0002965689,0.001606006,0.0009461922,0.0009843648,0.1853166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001205454,"about_ca_system_score_gemma":0.001887335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005925758,"about_ca_topic_score_gemma":0.009498087,"domain_scores_codex":[0.9994307,0.00005953263,0.0001193848,0.000164373,0.0001428845,0.00008308913],"domain_scores_gemma":[0.9910665,0.00620573,0.0006413914,0.0005111624,0.001199414,0.000375737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.001499529,0.00023209,0.003240628,0.007706645,0.00009587828,0.0002753648,0.0001318861,0.0007796585,0.001183356,0.0009346944,0.9633584,0.02056188],"study_design_scores_gemma":[0.01254902,0.001143307,0.04032904,0.005797983,0.0003604933,0.001616051,0.0006319678,0.003613984,0.005897074,0.01218376,0.915534,0.0003432992],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.0002910249,0.00003233732,0.0003622505,0.0001299519,0.00005216693,0.0001075487,0.9978312,0.0004355251,0.0007580785],"genre_scores_gemma":[0.009972409,0.0002816382,0.004873036,0.0008214423,0.00015278,0.002580068,0.968623,0.001127614,0.01156811],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8899521,"threshold_uncertainty_score":0.15697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02645936789123355,"score_gpt":0.2822577802042907,"score_spread":0.2557984123130571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}