{"id":"W6939652914","doi":"10.6084/m9.figshare.26630110.v1","title":"Additional file 3 of Autoimmune PaneLs as PrEdictors of Toxicity in Patients TReated with Immune Checkpoint InhibiTors (ALERT)","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto General Hospital; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Toxicity; Immunotherapy; Immune checkpoint; Immune system; Adverse effect; Pembrolizumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001427155,0.001026931,0.001485051,0.001925814,0.0006538879,0.001642244,0.001400618,0.001130923,0.8505583],"category_scores_gemma":[0.03775467,0.0004768842,0.001276007,0.003097327,0.0001767714,0.001657218,0.0009307732,0.000950197,0.1172531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009764038,"about_ca_system_score_gemma":0.00148701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007135904,"about_ca_topic_score_gemma":0.00985689,"domain_scores_codex":[0.9990368,0.0001904471,0.0002426785,0.0002218346,0.0001653903,0.0001427638],"domain_scores_gemma":[0.9726977,0.02055676,0.002358908,0.001128328,0.002679928,0.0005784624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.001009287,0.0001004578,0.007227181,0.004308866,0.0001519649,0.00009690599,0.00005601145,0.0004875819,0.00008259818,0.0005833255,0.9743274,0.01156852],"study_design_scores_gemma":[0.01762153,0.0008494708,0.1276983,0.01357692,0.001089983,0.001878294,0.0007763297,0.004663538,0.001325379,0.02045104,0.8097507,0.0003185172],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.0003513487,0.00003718773,0.0001532443,0.0001234064,0.00002409795,0.00007430027,0.9980953,0.0001508531,0.0009902811],"genre_scores_gemma":[0.02231914,0.0003120946,0.002855011,0.001234804,0.0002844235,0.002667902,0.953402,0.0008229799,0.01610165],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8505583,"threshold_uncertainty_score":0.2131604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01324502771502336,"score_gpt":0.2284430598144765,"score_spread":0.2151980320994531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}