{"id":"W6939976160","doi":"10.6084/m9.figshare.c.5938833.v1","title":"Safety, tolerability, and efficacy of monoclonal CD38 antibody felzartamab in late antibody-mediated renal allograft rejection: study protocol for a phase 2 trial","year":2022,"lang":"en","type":"other","venue":"Figshare","topic":"Mycorrhizal Fungi and Plant Interactions","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Monoclonal antibody; Tolerability; Placebo; Clinical trial; Surrogate endpoint; Antibody; Kidney transplantation; Monoclonal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01127627,0.004619709,0.00601103,0.0009011891,0.001735438,0.002257613,0.002679106,0.00492678,0.02488021],"category_scores_gemma":[0.006869498,0.001709955,0.002452198,0.0010163,0.002070765,0.002267668,0.00101288,0.00503791,0.005847252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002128574,"about_ca_system_score_gemma":0.008023519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008916567,"about_ca_topic_score_gemma":0.002289476,"domain_scores_codex":[0.9950384,0.002847748,0.0003416576,0.0005362275,0.0004626641,0.0007733047],"domain_scores_gemma":[0.9959002,0.0006771752,0.0008799257,0.0005475236,0.0006525298,0.001342667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9526743,0.01970265,0.0006076102,0.001759224,0.0004326052,0.0001302956,0.0001045319,0.0007839982,0.00645725,0.0005255562,0.004054039,0.01276794],"study_design_scores_gemma":[0.9208687,0.06920586,0.001160023,0.0001540479,0.0002274588,0.00004945435,0.00002480276,0.0005067944,0.000786298,0.0004341986,0.006549316,0.00003306873],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.09271239,0.00195595,0.004181466,0.001011854,0.0007612731,0.889074,0.004746369,0.0003832656,0.005173474],"genre_scores_gemma":[0.08441354,0.001326591,0.005996299,0.001643749,0.0004578415,0.8988461,0.001959516,0.00004822039,0.005308082],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02488021,"threshold_uncertainty_score":0.08323258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04251286184849778,"score_gpt":0.3467278995526759,"score_spread":0.3042150377041781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}