{"id":"W6940150331","doi":"10.6084/m9.figshare.c.6581522","title":"The effect of guselkumab on inhibiting radiographic progression in patients with active psoriatic arthritis: study protocol for APEX, a Phase 3b, multicenter, randomized, double-blind, placebo-controlled trial","year":2023,"lang":"en","type":"other","venue":"Figshare","topic":"Mycorrhizal Fungi and Plant Interactions","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Psoriatic arthritis; Rheumatology; Placebo; Radiography; Randomized controlled trial; Arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01287543,0.004515587,0.005839888,0.0009807261,0.001864919,0.002285419,0.002806967,0.004705238,0.02673033],"category_scores_gemma":[0.00914322,0.001884672,0.003601951,0.001373695,0.002221491,0.002169887,0.00106318,0.006177707,0.005935994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001775039,"about_ca_system_score_gemma":0.008624101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009731848,"about_ca_topic_score_gemma":0.002725444,"domain_scores_codex":[0.9944582,0.003086679,0.0005212354,0.0006468196,0.0006102726,0.0006767533],"domain_scores_gemma":[0.995808,0.00081825,0.0008817957,0.0004736767,0.000744431,0.001273863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9654268,0.008420195,0.0005192437,0.003966094,0.0007423798,0.0001148777,0.00008361073,0.0004664237,0.002618163,0.0005650527,0.005153439,0.01192359],"study_design_scores_gemma":[0.9752941,0.01870208,0.0008032161,0.000209286,0.0002763279,0.00002991339,0.00001860531,0.0003178644,0.000296965,0.0002785798,0.003753302,0.0000197122],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.05184326,0.00417321,0.004291095,0.001472125,0.001265501,0.9244732,0.007242928,0.0003662776,0.004872377],"genre_scores_gemma":[0.05981997,0.001991352,0.007808147,0.002090308,0.0004992815,0.9223589,0.002478474,0.00004556967,0.002907991],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02673033,"threshold_uncertainty_score":0.08942187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02201315556059557,"score_gpt":0.3114507088912405,"score_spread":0.2894375533306449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}