{"id":"W6944177310","doi":"10.17863/cam.23409","title":"CRISPR/Cas9 knockouts reveal genetic interaction between strain-transcendent erythrocyte determinants of Plasmodium falciparum invasion.","year":2017,"lang":"en","type":"article","venue":"Apollo (University of Cambridge)","topic":"Malaria Research and Control","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cambridge Institute for Medical Research, University of Cambridge; Canadian Institutes of Health Research; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Bill and Melinda Gates Foundation; Broad Institute; Wellcome Trust; University of Glasgow; National Institutes of Health; National Science Foundation","keywords":"Nucleofection; TSG101; Fusible alloy; Population","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001839983,0.0004776885,0.0002937134,0.0003167922,0.0001488119,0.0003263614,0.0003995326,0.0004750319,0.001891],"category_scores_gemma":[0.0002141645,0.0002644009,0.0003097437,0.0001344922,0.0003349948,0.0001450382,0.0004062217,0.0008871919,0.0007496139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003340789,"about_ca_system_score_gemma":0.0002022052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007419028,"about_ca_topic_score_gemma":0.00144573,"domain_scores_codex":[0.9997469,0.00002612321,0.00003519321,0.00006322822,0.00009177586,0.0000368305],"domain_scores_gemma":[0.9997395,0.00005730746,0.00009703657,0.0000288496,0.00001375513,0.00006359992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004926712,0.00001508027,0.0001183933,0.00002677312,0.000008100676,0.0001138351,0.00001399825,0.00007429683,0.9982109,0.0002004924,0.00008043568,0.001088389],"study_design_scores_gemma":[0.00001987911,0.0001148576,0.003705912,0.000009400762,0.00002470812,0.0007343054,0.00002528233,0.002579741,0.9862017,0.00008716297,0.006482105,0.00001496435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9550491,0.0009010521,0.03567173,0.0002173589,0.000117145,0.0001485159,0.00261263,0.001380917,0.003901588],"genre_scores_gemma":[0.9767148,0.0004675146,0.0150849,0.0001183892,0.000008867118,0.00008734864,0.001580319,0.0002640189,0.005673811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001891,"threshold_uncertainty_score":0.00632596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03663277729220751,"score_gpt":0.292546184469484,"score_spread":0.2559134071772765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}