{"id":"W6944849601","doi":"10.24433/co.1737239.v1","title":"The fitness cost of metallo-β-lactamase expression is a potential target for new therapeutic approaches to carbapenem resistance (Genetic Suppressors - Keio Collection)","year":2024,"lang":"en","type":"other","venue":"Code Ocean","topic":"Species Distribution and Climate Change","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Gene; Plasmid; Suppressor; Vector (molecular biology); Gene expression; Mutation; Gene deletion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001824696,0.0004601962,0.0003747284,0.0005089061,0.0002812513,0.0005658463,0.0003878083,0.0002932274,0.004619275],"category_scores_gemma":[0.0003305357,0.0001929852,0.0002487772,0.0004134667,0.0002131455,0.0002864275,0.0005451252,0.0009333409,0.0009585511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000397389,"about_ca_system_score_gemma":0.0003243109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001126489,"about_ca_topic_score_gemma":0.001986447,"domain_scores_codex":[0.9998478,0.00001869967,0.00001897988,0.00002959272,0.00005144689,0.00003344097],"domain_scores_gemma":[0.9997852,0.00004850443,0.00006111628,0.00002909757,0.0000261457,0.0000498964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006524732,0.00003501064,0.0009238584,0.00003204266,0.000005584127,0.00004202619,0.00001104198,0.00007263442,0.9941452,0.0003368836,0.0003305216,0.003999846],"study_design_scores_gemma":[0.00003618947,0.0004202007,0.02650333,0.00002042181,0.00005094595,0.001115822,0.00008906442,0.001621017,0.9458815,0.000416189,0.02382935,0.00001590219],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9744185,0.0013137,0.01053193,0.0007510397,0.00008514279,0.00008609362,0.003546982,0.000670853,0.008595805],"genre_scores_gemma":[0.970296,0.001206189,0.01269268,0.0001045987,0.00002758587,0.0001015377,0.005945812,0.0002572344,0.00936844],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.004619275,"threshold_uncertainty_score":0.01545298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06386840614129753,"score_gpt":0.2560612395633085,"score_spread":0.1921928334220109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}