{"id":"W6945603030","doi":"10.25418/crick.15363681.v1","title":"Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells","year":2018,"lang":"en","type":"article","venue":"Figshare","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; Australian Research Council; Biotechnology and Biological Sciences Research Council; Medical Research Council; Azrieli Foundation; Bundesministerium für Bildung und Forschung; National Institutes of Health; Directorate for Biological Sciences; Österreichischen Akademie der Wissenschaften; Deutsche Forschungsgemeinschaft; Stem Cells Australia; Rosetrees Trust; European Commission; Exzellenzclusters Entzündungsforschung; California Institute for Regenerative Medicine","keywords":"Embryoid body; Induced pluripotent stem cell; Teratoma; Embryonic stem cell; Cellular differentiation; Transcriptome; Stem cell; Germ layer; Regenerative medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002484213,0.0009343406,0.0003953373,0.00231606,0.0004981943,0.000579163,0.0006707266,0.0008104429,0.002324982],"category_scores_gemma":[0.002135949,0.0002929382,0.0005459795,0.001241414,0.000588689,0.0005773666,0.0009430867,0.001515588,0.001216492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003946379,"about_ca_system_score_gemma":0.0004328053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003439067,"about_ca_topic_score_gemma":0.001083232,"domain_scores_codex":[0.9973284,0.0006588245,0.0003272281,0.0003082899,0.001267806,0.0001094156],"domain_scores_gemma":[0.9977254,0.0008259448,0.0003821715,0.0003093502,0.0006650648,0.00009206424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007066214,0.0000743198,0.001849284,0.0003612749,0.00003100626,0.00007796995,0.0001222759,0.0002131821,0.9737781,0.0009045595,0.0003469148,0.02217043],"study_design_scores_gemma":[0.00001047551,0.0003351336,0.009759532,0.00004769757,0.00008119993,0.0005022814,0.00005779327,0.001106001,0.9777803,0.0004513601,0.009841181,0.00002700529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.269143,0.02254842,0.6784272,0.0005456508,0.0003933839,0.002251772,0.004049764,0.001367845,0.02127303],"genre_scores_gemma":[0.5070515,0.0212193,0.4441616,0.0004518533,0.0001569718,0.004223203,0.007291997,0.0004099543,0.01503356],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002484213,"threshold_uncertainty_score":0.01313794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02632272150867079,"score_gpt":0.295637404095538,"score_spread":0.2693146825868672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}