{"id":"W6948193803","doi":"10.5061/dryad.q573n5tr8","title":"Data from: Self-amplifying RNA generated with the modified nucleotides 5-methylcytidine and 5-methyluridine mediate strong expression and immunogenicity in vivo","year":2024,"lang":"en","type":"dataset","venue":"DRYAD","topic":"Subterranean biodiversity and taxonomy","field":"Earth and Planetary Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"RNA; Nucleotide; Immunogenicity; Gene expression; Messenger RNA; Guanosine; Gene; Intron; Immune system; Uridine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005473665,0.0003725362,0.0004093905,0.0001662286,0.0002895181,0.000304147,0.0007798633,0.0002183125,0.001204375],"category_scores_gemma":[0.00003240143,0.0002366445,0.00002970376,0.00026726,0.0001830291,0.0003541886,0.0003536381,0.0006402922,0.0001585058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009404843,"about_ca_system_score_gemma":0.00007283894,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01234157,"about_ca_topic_score_gemma":0.0177202,"domain_scores_codex":[0.9980907,0.0002004562,0.0002608503,0.0008068744,0.0002986476,0.0003424025],"domain_scores_gemma":[0.9985259,0.000421345,0.0001526697,0.0007488391,0.00002038211,0.0001308399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003159353,0.00003095926,0.00523478,0.0001617379,0.0002614102,0.000211082,0.0002456347,0.0001586816,0.000504689,4.896842e-7,0.991558,0.00131659],"study_design_scores_gemma":[0.001641211,0.0001581706,0.009152337,0.0003527467,0.0005127328,0.00002572237,0.000619006,0.01073173,0.0007461892,0.00003579264,0.9751348,0.0008895308],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.2427403,0.004748624,0.000006796149,0.0001301993,0.00019834,0.000250054,0.7518064,0.00003634612,0.00008297407],"genre_scores_gemma":[0.05396096,0.002906288,0.0005811832,0.0001340598,0.0002451587,0.000002727563,0.9421412,0.000008377453,0.00002005685],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.1903348,"threshold_uncertainty_score":0.9997087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0569255306875882,"score_gpt":0.2307487306428719,"score_spread":0.1738231999552837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}