{"id":"W6948193803","doi":"10.5061/dryad.q573n5tr8","title":"Data from: Self-amplifying RNA generated with the modified nucleotides 5-methylcytidine and 5-methyluridine mediate strong expression and immunogenicity in vivo","year":2024,"lang":"en","type":"dataset","venue":"DRYAD","topic":"Subterranean biodiversity and taxonomy","field":"Earth and Planetary Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"RNA; Nucleotide; Immunogenicity; Gene expression; Messenger RNA; Guanosine; Gene; Intron; Immune system; Uridine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001008492,0.002168562,0.00208289,0.004446408,0.000901335,0.002380264,0.001965158,0.001559249,0.07730743],"category_scores_gemma":[0.006116615,0.0005353112,0.00139131,0.01021832,0.0004752188,0.001019219,0.00175482,0.001533105,0.05740953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001366497,"about_ca_system_score_gemma":0.003053079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02202171,"about_ca_topic_score_gemma":0.03844601,"domain_scores_codex":[0.9988771,0.0001687616,0.0001925057,0.0003570919,0.0002474912,0.0001570859],"domain_scores_gemma":[0.9976326,0.000993327,0.0003206459,0.0002624979,0.0005489119,0.000241931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000381727,0.00004916165,0.00330147,0.01526584,0.0003109314,0.00009825379,0.0001406786,0.0009255321,0.001070771,0.0009708738,0.96903,0.008454742],"study_design_scores_gemma":[0.0004066295,0.0000289995,0.006850856,0.001302566,0.0001379833,0.00007244736,0.0001082123,0.0002464167,0.0005098332,0.0006072593,0.9896972,0.00003174516],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0001591673,0.0001580296,0.00003342698,0.00002541102,0.000008890304,0.000009974128,0.999049,0.0001022955,0.000453715],"genre_scores_gemma":[0.0005895359,0.0002072172,0.0002603465,0.00003228745,0.000002960834,0.00009214539,0.9983478,0.00005423342,0.0004135668],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.07730743,"threshold_uncertainty_score":0.2586191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0569255306875882,"score_gpt":0.2307487306428719,"score_spread":0.1738231999552837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}