{"id":"W6950331933","doi":"10.5281/zenodo.6524616","title":"Quality Control Characterization of α-Synuclein Preformed Fibrils (PFFs)","year":2019,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Fibril; Thioflavin; Characterization (materials science); Amyloid fibril; Electron microscope; Atomic force microscopy; Sonication; Amyloid (mycology)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001992634,0.0009230513,0.0005534706,0.001386514,0.0009506023,0.0006325651,0.0007320079,0.0007200179,0.005751763],"category_scores_gemma":[0.002690276,0.0004868586,0.0005199327,0.0009443082,0.0005897133,0.0005874221,0.0004098344,0.001074377,0.003281868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004863305,"about_ca_system_score_gemma":0.0005799013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001861326,"about_ca_topic_score_gemma":0.00289314,"domain_scores_codex":[0.998879,0.0001329812,0.0001428197,0.0002425097,0.0004848333,0.0001178152],"domain_scores_gemma":[0.9973967,0.0003851275,0.0001949137,0.0005772728,0.001366,0.00007993727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007043335,0.00004160914,0.0004040289,0.0001606578,0.00001473939,0.0001178147,0.0001519739,0.000141169,0.9887908,0.0003544308,0.001118074,0.008634268],"study_design_scores_gemma":[0.00002391371,0.0001423035,0.003891387,0.00007189671,0.00004749726,0.0004322318,0.00006855448,0.001154156,0.9653839,0.0002577056,0.02849612,0.00003026553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3361097,0.007439837,0.6101086,0.0009316498,0.0008402054,0.006278599,0.01782385,0.005549649,0.01491792],"genre_scores_gemma":[0.3632951,0.009224541,0.5292593,0.0007454166,0.0001808507,0.009372786,0.0503039,0.003564275,0.03405384],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.005751763,"threshold_uncertainty_score":0.01924157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02955723255428264,"score_gpt":0.2671481853287468,"score_spread":0.2375909527744642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}