{"id":"W6958042521","doi":"10.60692/vcdgp-8vp26","title":"Phase III HEAT Study Adding Lyso-Thermosensitive Liposomal Doxorubicin to Radiofrequency Ablation in Patients with Unresectable Hepatocellular Carcinoma Lesions","year":2018,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Radiofrequency ablation; Hepatocellular carcinoma; Clinical endpoint; Confidence interval; Doxorubicin; Target lesion; Lesion; Phases of clinical research; Thermal ablation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001751627,0.001161601,0.002408089,0.0003218665,0.0002802059,0.0008203756,0.0006311523,0.001083536,0.002790943],"category_scores_gemma":[0.001228678,0.0005234071,0.001743841,0.000326499,0.000869657,0.0006794834,0.0003091407,0.002298321,0.0005237163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000761611,"about_ca_system_score_gemma":0.001337037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000886976,"about_ca_topic_score_gemma":0.001458158,"domain_scores_codex":[0.9994619,0.0003026068,0.00002547955,0.00007383054,0.00004507721,0.0000910298],"domain_scores_gemma":[0.9992085,0.0002227502,0.0002026204,0.00009331943,0.00005821164,0.0002145867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9167171,0.02498901,0.002590664,0.0006235348,0.001483351,0.00006455201,0.0001259035,0.001535522,0.01844349,0.0001092378,0.0009855796,0.03233197],"study_design_scores_gemma":[0.5972714,0.3935339,0.005241854,0.00002243389,0.0004885723,0.00004808445,0.00003301722,0.000615072,0.001934926,0.00006942848,0.000725181,0.00001612176],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994114,0.001925223,0.0006479763,0.0002937047,0.0001539352,0.001732878,0.0004301012,0.00007059427,0.0006316739],"genre_scores_gemma":[0.9921139,0.00148137,0.0009613425,0.0005855129,0.0002631445,0.002542497,0.0006864236,0.00002199714,0.001343786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002790943,"threshold_uncertainty_score":0.009336591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04439312577259016,"score_gpt":0.2347001711734605,"score_spread":0.1903070454008704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}