{"id":"W6958284978","doi":"10.6084/m9.figshare.20381760","title":"Additional file 2 of Copper ions, prion protein and Aβ modulate Ca levels in central nervous system myelin in an NMDA receptor-dependent manner","year":2022,"lang":"en","type":"article","venue":"Figshare","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Corpus callosum; Myelin; White matter; Central nervous system; Amyloid (mycology); Prion protein; Myelin basic protein; In vivo; Proteolipid protein 1","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001875416,0.001804948,0.002303643,0.002352567,0.001359286,0.002897453,0.002413928,0.001692932,0.9235246],"category_scores_gemma":[0.02408468,0.001015719,0.001400278,0.004246972,0.00041915,0.00269655,0.001429396,0.001210391,0.2534551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001168017,"about_ca_system_score_gemma":0.002242298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005062974,"about_ca_topic_score_gemma":0.007952393,"domain_scores_codex":[0.9992241,0.00009232008,0.0001553902,0.0001937282,0.0001973144,0.0001371653],"domain_scores_gemma":[0.9828587,0.01265803,0.001005315,0.0009016056,0.001987455,0.0005890153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008559977,0.0001669789,0.002274996,0.01061395,0.00009709571,0.0002227578,0.0001132909,0.0004775064,0.0006537559,0.001059445,0.9738442,0.009620001],"study_design_scores_gemma":[0.01442602,0.0008331841,0.03127988,0.008050676,0.0003764428,0.0009531077,0.0004738578,0.002057257,0.003140978,0.01406857,0.9240275,0.0003125255],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.000178622,0.0000288318,0.0002644793,0.0001001611,0.00004580331,0.0001192117,0.9979694,0.0004317666,0.0008616564],"genre_scores_gemma":[0.009334015,0.0003190082,0.00585159,0.00068241,0.0001529034,0.003213553,0.9662278,0.002118599,0.01210021],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9235246,"threshold_uncertainty_score":0.1090829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01590830732954753,"score_gpt":0.2270802951449142,"score_spread":0.2111719878153666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}