{"id":"W6958482739","doi":"10.6084/m9.figshare.c.6594872","title":"Adiponectin deficiency accelerates brain aging via mitochondria-associated neuroinflammation","year":2023,"lang":"en","type":"other","venue":"Figshare","topic":"Genetic diversity and population structure","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Neuroinflammation; Adiponectin; Adipokine; Aging brain; Mitochondrion; Agonist; Inflammation; Brain aging; AMPK","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002252554,0.0005434059,0.000369301,0.0007395652,0.0002232305,0.0004189574,0.0004985385,0.0003016318,0.02197578],"category_scores_gemma":[0.0001172817,0.0002086424,0.0003059288,0.0004171734,0.000238006,0.0002738023,0.0003968316,0.0006508752,0.004543258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002512474,"about_ca_system_score_gemma":0.0001630506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002318216,"about_ca_topic_score_gemma":0.0003925846,"domain_scores_codex":[0.9998778,0.00001808317,0.00001096467,0.00003194515,0.00003422746,0.00002695956],"domain_scores_gemma":[0.9999099,0.00000934558,0.00002837227,0.00001770232,0.00001083947,0.00002387839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007255464,0.0001379628,0.0003951531,0.0001800142,0.00002180715,0.0001934666,0.00001934722,0.0001598303,0.9804822,0.001494872,0.001816851,0.01437291],"study_design_scores_gemma":[0.0002348529,0.0007732353,0.012931,0.00006302133,0.00008675612,0.0006631766,0.00006168815,0.002237201,0.9284225,0.001565881,0.0529367,0.00002399047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.8848292,0.008805216,0.04402544,0.002154752,0.0008825211,0.0002179289,0.01579563,0.00470149,0.03858785],"genre_scores_gemma":[0.8929341,0.006448031,0.01691967,0.0004713369,0.0001013841,0.0002112139,0.007410283,0.0005532308,0.07495078],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.02197578,"threshold_uncertainty_score":0.07351631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02196769903322451,"score_gpt":0.247659745627058,"score_spread":0.2256920465938335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}