{"id":"W6958538041","doi":"10.6084/m9.figshare.12420932","title":"Tucatinib: First Approval","year":2020,"lang":"en","type":"other","venue":"Figshare","topic":"Scientific Computing and Data Management","field":"Decision Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Drug approval; Breast cancer; Drug industry; Peer review; Human use; Ethical issues","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003294628,0.0002161591,0.0003009742,0.0003032043,0.00009320029,0.0007243258,0.002410871,0.0001263169,0.8804069],"category_scores_gemma":[0.01047396,0.0001661929,0.0001432191,0.0008450744,0.00001062954,0.00005093496,0.001268578,0.0001725093,0.2195733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001513987,"about_ca_system_score_gemma":0.00006817496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002108563,"about_ca_topic_score_gemma":0.00008125831,"domain_scores_codex":[0.9967984,0.00005450584,0.0003532727,0.001136868,0.001413384,0.0002435949],"domain_scores_gemma":[0.9973062,0.0004372966,0.0003788823,0.001653078,0.00005781845,0.0001667161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[7.259397e-7,0.00001088374,0.000002543381,0.00004214125,0.000009621151,0.00001332421,0.0000435027,0.000003347956,2.993005e-8,0.00001948559,0.9788973,0.02095708],"study_design_scores_gemma":[0.00007291362,0.000009803391,0.00005894657,0.0006161022,0.000004253253,0.000001338476,0.00004517916,0.000640467,9.66589e-7,0.00009802177,0.9982522,0.0001998478],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[3.730474e-8,0.0001935465,0.0000249264,0.0004601109,0.0006555268,0.0002124493,0.2498665,0.0002972636,0.7482896],"genre_scores_gemma":[0.00003234177,9.727689e-7,0.0006389027,0.0004460664,0.0008697721,0.00004872625,0.08868027,0.000152627,0.9091303],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.6608337,"threshold_uncertainty_score":0.9978613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3020782037667714,"score_gpt":0.3895391972480569,"score_spread":0.08746099348128544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}