{"id":"W6958541172","doi":"10.6084/m9.figshare.26630104.v1","title":"Additional file 1 of Autoimmune PaneLs as PrEdictors of Toxicity in Patients TReated with Immune Checkpoint InhibiTors (ALERT)","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto General Hospital; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Toxicity; Antigen; Immune system; Immunotherapy; Pembrolizumab; Immune checkpoint; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001412529,0.0009560538,0.001230085,0.002039851,0.0006320378,0.00152334,0.001257063,0.001083091,0.8376133],"category_scores_gemma":[0.03265715,0.0004580308,0.001006373,0.002993355,0.0001838712,0.001330751,0.0007685631,0.0008651744,0.1203106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008451263,"about_ca_system_score_gemma":0.001368765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004865455,"about_ca_topic_score_gemma":0.007947301,"domain_scores_codex":[0.9991486,0.000177582,0.0001742727,0.0002239935,0.0001554081,0.0001200585],"domain_scores_gemma":[0.9683765,0.02533904,0.001784098,0.001164676,0.002750322,0.0005853031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0005672805,0.00009646358,0.004937475,0.003420039,0.0000878801,0.00008875986,0.00005090453,0.0004029719,0.0001584679,0.0004272542,0.9778404,0.01192214],"study_design_scores_gemma":[0.009583025,0.0007011489,0.108058,0.007638386,0.0006761928,0.001700718,0.0007169371,0.004093349,0.001989194,0.01657746,0.8479948,0.0002708892],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.0003276138,0.00003483746,0.0002292413,0.0001284273,0.0000283397,0.00006604246,0.9981888,0.0001867145,0.0008099883],"genre_scores_gemma":[0.01638656,0.0002929586,0.004087985,0.001114176,0.0002663125,0.002345857,0.9633343,0.0007412579,0.01143068],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8376133,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01349073088109061,"score_gpt":0.2287932213616845,"score_spread":0.2153024904805939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}