{"id":"W6958735083","doi":"10.6084/m9.figshare.c.7908244","title":"The endocannabinoidome–gut microbiome–brain axis as a novel therapeutic target for autism spectrum disorder","year":2025,"lang":"en","type":"other","venue":"Figshare","topic":"Plant pathogens and resistance mechanisms","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; McGill University","funders":"","keywords":"Endocannabinoid system; Palmitoylethanolamide; Autism spectrum disorder; Metabotropic glutamate receptor 5; Monoacylglycerol lipase; Gut–brain axis; Cannabinoid receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001817646,0.000396186,0.0005426976,0.0004628925,0.0001466186,0.0004935511,0.0002604384,0.0006316554,0.005640777],"category_scores_gemma":[0.0002080011,0.00007932988,0.0005213425,0.0001992494,0.0001597706,0.0003334113,0.0003767327,0.00111676,0.0008191976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003572259,"about_ca_system_score_gemma":0.00048825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006721814,"about_ca_topic_score_gemma":0.001610719,"domain_scores_codex":[0.9999216,0.00001796776,0.000008222953,0.00001460442,0.00002253524,0.00001508685],"domain_scores_gemma":[0.9999347,0.0000139488,0.00001411752,0.000002271552,0.00002340863,0.0000116415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00114012,0.0002578234,0.001161653,0.01525654,0.0004258226,0.001230269,0.0001417655,0.000698404,0.09478799,0.009389896,0.0432601,0.8322496],"study_design_scores_gemma":[0.0004948988,0.001843403,0.01025515,0.004792488,0.0009139237,0.004016405,0.000287319,0.001209101,0.02485872,0.008343911,0.9429057,0.00007892431],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01522405,0.9616823,0.003625994,0.005167959,0.001631694,0.00006922919,0.0004214565,0.000202178,0.01197524],"genre_scores_gemma":[0.1199211,0.8580019,0.00574206,0.003414134,0.001197759,0.0001639709,0.0007729959,0.00003141226,0.01075459],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005640777,"threshold_uncertainty_score":0.01887029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01443079504115561,"score_gpt":0.2194740806767323,"score_spread":0.2050432856355767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}