{"id":"W6958951376","doi":"10.6084/m9.figshare.c.6836220.v1","title":"MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands","year":2023,"lang":"en","type":"other","venue":"Figshare","topic":"Botanical Research and Chemistry","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Inflammation; Oxidative stress; Inflammasome; Lipopolysaccharide; Mastitis; Pyrin domain; microRNA; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002276692,0.0003117289,0.0003301206,0.0002306558,0.0001906324,0.0003781251,0.0001328796,0.0002825118,0.0007360304],"category_scores_gemma":[0.0001530856,0.0001968929,0.000317815,0.0001509832,0.0002226924,0.0001775959,0.0001843137,0.0006209876,0.0003168315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002598619,"about_ca_system_score_gemma":0.0002274856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003793775,"about_ca_topic_score_gemma":0.0005603704,"domain_scores_codex":[0.9997415,0.00004283144,0.0000312558,0.0000541435,0.00007773454,0.00005258157],"domain_scores_gemma":[0.9999011,0.000009307216,0.00003931342,0.000009110867,0.000020593,0.00002051866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001782791,0.00002903047,0.0001712721,0.00006370229,0.000005943998,0.0000210957,0.00001644093,0.00002775126,0.9986545,0.00005212554,0.00005283291,0.0007269388],"study_design_scores_gemma":[0.00003958413,0.0005380663,0.006686515,0.00001496812,0.00005503002,0.0002475812,0.00007497743,0.00126075,0.9861493,0.00007066858,0.004853994,0.000008611206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829639,0.007628758,0.00555503,0.0002600808,0.0001379562,0.00007452676,0.0008133818,0.0002434739,0.002322944],"genre_scores_gemma":[0.992593,0.001590885,0.003070171,0.0001382543,0.00001754264,0.00008959977,0.0005745949,0.00002934938,0.001896475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007360304,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02126396081280843,"score_gpt":0.2384251736099862,"score_spread":0.2171612127971778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}