{"id":"W6959001337","doi":"10.6084/m9.figshare.c.7591167","title":"Integrated safety analysis of tofacitinib from Phase 2 and 3 trials of patients with ankylosing spondylitis","year":2024,"lang":"en","type":"other","venue":"Figshare","topic":"Hibiscus Plant Research Studies","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pfizer (Canada)","funders":"","keywords":"Tofacitinib; Ankylosing spondylitis; Rheumatoid arthritis; Adverse effect; Placebo; Cohort; Randomized controlled trial; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003700443,0.0003316985,0.001573499,0.000780391,0.00003769598,0.0000160332,0.0001897325,0.0004607466,0.8397638],"category_scores_gemma":[0.00157125,0.0002330094,0.0002345219,0.0007429519,0.00008917536,0.00003227976,0.0001461092,0.0005869077,0.000111765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003694744,"about_ca_system_score_gemma":0.0001095963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001663892,"about_ca_topic_score_gemma":0.0002492949,"domain_scores_codex":[0.9976674,0.0006780183,0.0006740724,0.0004215249,0.000287026,0.0002719777],"domain_scores_gemma":[0.997601,0.001271242,0.0005863087,0.0002171242,0.0001931812,0.0001311247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00122505,0.0002570508,0.001329398,0.0009003545,0.01450386,0.00005191391,0.0003424711,0.000003399447,0.00007906788,0.000005551565,0.970654,0.0106479],"study_design_scores_gemma":[0.002267071,0.0001233218,0.0007160369,0.002155851,0.003521921,2.994425e-7,0.00004964738,0.00009279614,0.0007703314,0.000006380561,0.9900755,0.0002208393],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.003638843,0.004546002,9.738862e-7,0.00001730387,0.00007519293,0.0006679936,0.9622238,0.00005963932,0.02877026],"genre_scores_gemma":[0.002707413,0.0002235687,0.00006665206,0.00003845974,0.00008821049,0.00007612414,0.9713972,0.0001312885,0.02527113],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.839652,"threshold_uncertainty_score":0.9501849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2278174788460772,"score_gpt":0.4891693222444645,"score_spread":0.2613518433983872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}