{"id":"W6959193359","doi":"10.1016/j.jddst.2025.106960","title":"Exploring natural components in vaccine delivery systems: Types, routes of administration, in-vitro and in-vivo quantification techniques","year":2025,"lang":"en","type":"article","venue":"Journal of Drug Delivery Science and Technology","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Immunogenicity; Biopharmaceutical; Bioavailability; Site of action; Clinical trial; Immunization; Human use","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012544,0.0006185725,0.0005058436,0.0009285671,0.0002459358,0.0009694226,0.0003585549,0.0006200522,0.0008940574],"category_scores_gemma":[0.001061298,0.0003128636,0.0004527701,0.0008257571,0.0005626649,0.001720675,0.0003832695,0.001063102,0.0006212172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007107506,"about_ca_system_score_gemma":0.0007756219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000616494,"about_ca_topic_score_gemma":0.000770469,"domain_scores_codex":[0.9990988,0.0002394223,0.00006450062,0.0002019484,0.0003476189,0.00004768667],"domain_scores_gemma":[0.999587,0.0001487311,0.0001177525,0.00002898029,0.0001022377,0.00001536861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001153811,0.0001204307,0.0009647585,0.003171802,0.00004165102,0.0001070599,0.000124323,0.0007157135,0.8714471,0.002986582,0.000554821,0.1196503],"study_design_scores_gemma":[0.000009824856,0.0005792162,0.001841729,0.0002508758,0.0001046527,0.0005982862,0.00007977492,0.001571835,0.934175,0.00123594,0.05951568,0.00003726046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2088455,0.5155903,0.2532712,0.002170185,0.0007172133,0.0007747809,0.0008944871,0.00042384,0.01731248],"genre_scores_gemma":[0.4795767,0.3424232,0.1651379,0.001038538,0.0003811335,0.0007839034,0.0006977682,0.0001766986,0.009784146],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0012544,"threshold_uncertainty_score":0.006633937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08359995172325631,"score_gpt":0.36814536096802,"score_spread":0.2845454092447637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}