{"id":"W6959399332","doi":"10.1021/jo0355855.s001","title":"Conformationally Constrained Dipeptide Surrogates with\\nAromatic Side-Chains:  Synthesis of 4-Aryl Indolizidin-9-one\\nAmino Acids by Conjugate Addition to a Common\\nα,ω-Diaminoazelate Enone Intermediate","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Plant pathogens and resistance mechanisms","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stantec (Canada)","funders":"","keywords":"Dipeptide; Conjugate; Enone; Yield (engineering); Amine gas treating; Nucleophile; Hydrolysis; Aryl","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001831377,0.0004019394,0.000275687,0.0001234101,0.0001024331,0.0002163635,0.0004885109,0.0003152108,0.00160184],"category_scores_gemma":[0.000150771,0.0001856324,0.0001746008,0.0001763642,0.000128388,0.0002277235,0.0003053944,0.0005238531,0.001139437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003163877,"about_ca_system_score_gemma":0.0002330409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002819228,"about_ca_topic_score_gemma":0.0006285989,"domain_scores_codex":[0.999898,0.00001544488,0.00001014765,0.00002423265,0.00002236416,0.0000297788],"domain_scores_gemma":[0.9999117,0.000007486124,0.00002641287,0.000009716809,0.00001120054,0.00003348626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002041422,0.00004809597,0.00006622657,0.0001095051,0.000009845325,0.0001530616,0.00004671136,0.0007101395,0.9941844,0.0006561632,0.000101955,0.003709791],"study_design_scores_gemma":[0.00005562038,0.0006288182,0.0003387653,0.000009227057,0.00001605123,0.0001021208,0.00001377052,0.001026741,0.9918982,0.00007435394,0.005823171,0.00001320042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760162,0.001267555,0.01410622,0.0000870079,0.00007967074,0.0001774727,0.0005460017,0.0002047739,0.007515226],"genre_scores_gemma":[0.9822052,0.00100999,0.01019153,0.00004938889,0.00001185165,0.0001249603,0.0004667514,0.00005181783,0.005888475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00160184,"threshold_uncertainty_score":0.005358696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01526918621247051,"score_gpt":0.1884668854318899,"score_spread":0.1731976992194194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}