{"id":"W6959478596","doi":"10.1016/s1474-4422%2824%2900369-7","title":"Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021","year":2024,"lang":"en","type":"article","venue":"Repository@Hull (Worktribe) (University of Hull)","topic":"Genetic and Environmental Crop Studies","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Cilag; Precursory Research for Embryonic Science and Technology; Japan Science and Technology Agency; Novartis Pharma; Allergan; National Institutes of Health; European Stroke Organisation; Esperion Therapeutics; National Science and Technology Council; DSM Nutritional Products; Intas Pharmaceuticals; Lilly Deutschland; National Research, Development and Innovation Office; National Health and Medical Research Council; Neuraxpharm; Novo Nordisk Pharma; Ministry of Science and ICT, South Korea; Medical Research Council; African Academy of Sciences; Servier; Istituto Auxologico Italiano; University of Jordan; Novo Nordisk; Eisai; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Ministero della Salute; Generalitat de Catalunya; Ministry of Education, Culture, Sports, Science and Technology; Amryt Pharma; Australian Academy of Science; Johns Hopkins University; Amarin Corporation; Cardinal Health; Daiichi Sankyo Europe; Agios Pharmaceuticals; Regeneron Pharmaceuticals; Fondazione Cariplo; Fresenius Medical Care North America; Deutsche Forschungsgemeinschaft; Alzheimer's Association; Global Brain Health Institute; Idorsia Pharmaceuticals; H. Lundbeck A/S; International Hepato-Pancreato-Biliary Association; Government of Canada; Ultragenyx Pharmaceutical; Canadian Institutes of Health Research; Italfarmaco; Korean Diabetes Association; European Commission; AstraZeneca; International Atomic Energy Agency; Alexion Pharmaceuticals; National Research Foundation of Korea; Biogen; King Saud University; Bristol-Myers Squibb; Teva Pharmaceutical Industries; American Heart Association; Moderna; Bill and Melinda Gates Foundation; Pfizer; Amicus Therapeutics; Casen Recordati; Alexander von Humboldt-Stiftung; Japan Society for the Promotion of Science; Swedish Orphan Biovitrum; Astellas Pharma; Bayer; Cardiff University; U.S. Department of Defense; Eli Lilly and Company; AOSpine; Danone; American Diabetes Association; Sociedad Madrileña de Nefrología; National Research Foundation; Amgen; International Society of Travel Medicine; National Cerebral and Cardiovascular Center; Sanofi","keywords":"Stroke (engine); Burden of disease; Disease burden; Attributable risk; Quality-adjusted life year; Cause of death; Incidence (geometry); Disease; Disability-adjusted life year","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001894344,0.000136216,0.0003674097,0.0000210924,0.000332399,0.00002816213,0.0001950023,0.00005063111,0.00003461406],"category_scores_gemma":[0.00003232255,0.00006394681,0.0002164095,0.0004089755,0.000174233,0.00006430412,0.0001835952,0.0000430464,7.294205e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006165927,"about_ca_system_score_gemma":0.00001483696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002906331,"about_ca_topic_score_gemma":0.0003872501,"domain_scores_codex":[0.9988786,0.00010871,0.0002000343,0.0002973038,0.0003915896,0.0001237595],"domain_scores_gemma":[0.9992214,0.0003283305,0.0002049441,0.00007567898,0.0000857688,0.0000838599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005570237,0.0004924467,0.9736665,0.002294696,0.008471323,0.00003120717,0.00388099,0.004349798,0.002835,0.0007335086,0.001446468,0.00124099],"study_design_scores_gemma":[0.0003252437,0.0004613784,0.9497638,0.0003014386,0.003784049,0.000003781678,0.04075683,0.00379872,0.00002344536,0.0001383296,0.0004520531,0.0001909786],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899218,0.008415049,0.00003620834,0.0002790942,0.00004952619,0.0004881725,0.0007176545,0.000006947022,0.00008555037],"genre_scores_gemma":[0.9989061,0.0005496526,0.00003523346,0.000001570985,0.00005555454,0.000001802817,0.0000226032,7.18643e-7,0.000426781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03687584,"threshold_uncertainty_score":0.4393523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01613801970188521,"score_gpt":0.2049386508891862,"score_spread":0.1888006311873009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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