{"id":"W6959503105","doi":"10.1021/acsnano.3c09311.s001","title":"High-Performance\\nPlasma Biomarker Panel for Alzheimer’s\\nDisease Screening Using a Femtomolar-Level Label-Free Biosensing System","year":2023,"lang":"en","type":"article","venue":"Figshare","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biomarker; Cerebrospinal fluid; Disease; Amyloid (mycology); Amyloid β; Stage (stratigraphy); Biological fluids","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001280168,0.0006957949,0.0004400983,0.0009721553,0.0002960759,0.0006511084,0.0004725482,0.001118999,0.001391062],"category_scores_gemma":[0.001378816,0.0002232188,0.0004580969,0.0003255286,0.000216902,0.0004016056,0.0004893046,0.0006135906,0.0008577053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004187799,"about_ca_system_score_gemma":0.0004131426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007500995,"about_ca_topic_score_gemma":0.002544574,"domain_scores_codex":[0.9988406,0.0002468111,0.00005923908,0.0003541445,0.0004244811,0.00007461247],"domain_scores_gemma":[0.999615,0.0001079323,0.00005468762,0.00003370846,0.0001507663,0.00003792568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006523977,0.0004156052,0.0171824,0.0001889788,0.0001435877,0.0002056478,0.00009529933,0.001738211,0.8989196,0.0008786991,0.00295297,0.07662667],"study_design_scores_gemma":[0.0001199386,0.001529992,0.04599731,0.00008505618,0.0002679656,0.001911966,0.000100891,0.1102307,0.8144435,0.001124157,0.02402129,0.0001671976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6464955,0.006717253,0.3233058,0.001107706,0.0004528376,0.0009678403,0.002537182,0.004046851,0.01436898],"genre_scores_gemma":[0.7817841,0.001054307,0.2062846,0.00142083,0.0001218912,0.0005926349,0.001897383,0.00005728863,0.006787018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001391062,"threshold_uncertainty_score":0.006770313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3251527928726459,"score_gpt":0.3697893994376712,"score_spread":0.04463660656502533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}